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Elucidating the role of stress granules dynamics in the pathogenesis of ALS
https://braincanada.ca/fr/subventions-financées/elucidating-the-role-of-stress-granules-dynamics-in-the-pathogenesis-of-alsThe lifetime risk of developing amyotrophic lateral sclerosis (ALS) is approximately 1 in 350 for men and 1 in 440 for women, making it the most common adult-onset motor neuron disease. Project Overview The lifetime risk of developing amyotrophic lateral sclerosis (ALS) is approximately 1 in 350...
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EMPOW-HER: Exploring methods to improve participation of women in clinical trials to help enhance stroke recovery research
https://braincanada.ca/fr/subventions-financées/empow-her-exploring-methods-to-improve-participation-of-women-in-clinical-trials-to-help-enhance-stroke-recovery-researchIn general, women take part in research less than men. Project Overview In general, women take part in research less than men. We found women take part in our research less than men too. We are a team of rehabilitation researchers located across Canada that test new treatments like drugs,...
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Enabling Neuroscience research Approaches for Brain, feeLings and Emotions (ENABLE): An Platform for Clinical Trials in Mood Disorders
https://braincanada.ca/fr/subventions-financées/enabling-neuroscience-research-approaches-for-brain-feelings-and-emotions-enable-an-platform-for-clinical-trials-in-mood-disordersMood disorders such as depression and bipolar disorder affect over 350 million people around the world. Project Overview Mood disorders such as depression and bipolar disorder affect over 350 million people around the world. While several effective treatments exist, it is often difficult to match...
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Engaging neural stem cells for enhanced brain regeneration
https://braincanada.ca/fr/subventions-financées/engaging-neural-stem-cells-for-enhanced-brain-regenerationNeurological disorders affect more than 1 in 3 people, making them a leading cause of illness and disability worldwide. Project Overview Neurological disorders affect more than 1 in 3 people, making them a leading cause of illness and disability worldwide. Currently, there are no effective...
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Enhancing Support for Alzheimer’s Caregivers: A Comprehensive Approach to Caregiver Needs and Healthcare Integration Across the Disease Trajectory
https://braincanada.ca/fr/subventions-financées/enhancing-support-for-alzheimer-s-caregivers-a-comprehensive-approach-to-caregiver-needs-and-healthcare-integration-across-the-disease-trajectoryIn Canada, about 1.1 million people care for family members with dementia, providing support that saves the healthcare system billions each year. Project Overview In Canada, about 1.1 million people care for family members with dementia, providing support that saves the healthcare system billions...
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Enhancing Supports for Autistic Post-Secondary Students at the University of Calgary
https://braincanada.ca/fr/subventions-financées/enhancing-supports-for-autistic-post-secondary-students-at-the-university-of-calgaryAutistic individuals are disproportionately under-represented in post-secondary institutions, with only 35% of students with autism pursuing post-secondary education. Project Overview Autistic individuals are disproportionately under-represented in post-secondary institutions, with only 35% of...
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Enhancing the efficacy of heat shock protein inducers by cotreatment with a histone deacetylase inhibitor – A therapeutic strategy for ALS
https://braincanada.ca/fr/subventions-financées/enhancing-the-efficacy-of-heat-shock-protein-inducers-by-cotreatment-with-a-histone-deacetylase-inhibitor-a-therapeutic-strategy-for-alsIn ALS and many other neurodegenerative diseases, one of the defining characteristics is that proteins can become misfolded and clump together, potentially damaging nerve cells. Project Overview In ALS and many other neurodegenerative diseases, one of the defining characteristics is that proteins...
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Enhancing Therapeutic Responses to IDH Inhibitors in IDH Mutated Gliomas
https://braincanada.ca/fr/subventions-financées/enhancing-therapeutic-responses-to-idh-inhibitors-in-idh-mutated-gliomasGliomas are a type of brain tumor that pose a significant health concern due to their severity. Some of these tumors have alterations, known as mutations, in genes called IDH1 or IDH2 which affect how the tumor behaves and grows. Project Overview Gliomas are a type of brain tumor that pose a...
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Enhancing walking recovery after stroke through a 24-hour behaviour change approach
https://braincanada.ca/fr/subventions-financées/enhancing-walking-recovery-after-stroke-through-a-24-hour-behaviour-change-approachWe are looking at how a behaviour change program can help stroke survivors recover their ability to walk better. Project Overview We are looking at how a behaviour change program can help stroke survivors recover their ability to walk better. We are aiming to recruit 24 people who have had a stroke...
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Ensuring equitable access to inpatient rehabilitation for people living with dementia: An effectiveness-implementation randomized trial
https://braincanada.ca/fr/subventions-financées/ensuring-equitable-access-to-inpatient-rehabilitation-for-people-living-with-dementia-an-effectiveness-implementation-randomized-trialOne in five older adults with dementia is hospitalized each year. Project Overview One in five older adults with dementia is hospitalized each year. One in three hospitalized older adults will lose independence in transferring, eating, ambulating, dressing, or bathing, which increases nursing home...