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Deepening our understanding of G3BP1 and its paralog G3BP2 to facilitate accurate therapeutic development for ALS/FTD
https://braincanada.ca/fr/subventions-financées/deepening-our-understanding-of-g3bp1-and-its-paralog-g3bp2-to-facilitate-accurate-therapeutic-development-for-als-ftdWhile significant efforts have been made worldwide, the development of an effective therapy to significantly slow or halt ALS disease progression has remained elusive. Project Overview While significant efforts have been made worldwide, the development of an effective therapy to significantly slow...
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Defective protein translation: a causative pathway in ALS
https://braincanada.ca/fr/subventions-financées/defective-protein-translation-a-causative-pathway-in-alsAmyotrophic lateral sclerosis (ALS) is a nervous system disease that affects nerve cells (motor neurons) connecting muscle with the brain and spinal cord. Project Overview Amyotrophic lateral sclerosis (ALS) is a nervous system disease that affects nerve cells (motor neurons) connecting muscle with...
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Defective protein translation: a causative pathway in ALS?
https://braincanada.ca/fr/subventions-financées/defective-protein-translation-a-causative-pathway-in-als-2Almost all amyotrophic lateral sclerosis (ALS) is accompanied by neuronal cytoplasmic aggregates of TAR DNA-binding protein-43 (TDP-43). Project Overview Almost all amyotrophic lateral sclerosis (ALS) is accompanied by neuronal cytoplasmic aggregates of TAR DNA-binding protein-43 (TDP-43). TDP-43...
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Defining a cortical-subcortical circuit for impulse control in humans
https://braincanada.ca/fr/subventions-financées/defining-a-cortical-subcortical-circuit-for-impulse-control-in-humansAttention Deficit Hyperactivity Disorder (ADHD) is the most common brain-related condition in children leading to challenges with attention and impulse control. As a result, children often struggle to stay focused or stop themselves from acting impulsively. Project Overview Attention Deficit...
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Defining and targeting clonal hematopoiesis as a driver of glioblastoma growth
https://braincanada.ca/fr/subventions-financées/defining-and-targeting-clonal-hematopoiesis-as-a-driver-of-glioblastoma-growthWe discovered that approximately one fifth of people with the deadly brain tumour glioblastoma show age-related genetic changes in their blood cells called ‘clonal hematopoiesis’, or CHIP. Project Overview We discovered that approximately one fifth of people with the deadly brain tumour...
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Defining conserved functions of RNA binding proteins in stress-granule biogenesis
https://braincanada.ca/fr/subventions-financées/defining-conserved-functions-of-rna-binding-proteins-in-stress-granule-biogenesisRNA is a mobile form of genetic information that is made from our DNA and its complex regulation is extremely important to the proper functioning of our cells. Project Overview RNA is a mobile form of genetic information that is made from our DNA and its complex regulation is extremely important to...
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Defining the role of primary cilia in shaping astrocyte development and response to brain insults
https://braincanada.ca/fr/subventions-financées/defining-the-role-of-primary-cilia-in-shaping-astrocyte-development-and-response-to-brain-insultsAstrocytes are a major type of cells that react to brain activity, injuries and diseases to help support optimal brain functions. Project Overview Astrocytes are a major type of cells that react to brain activity, injuries and diseases to help support optimal brain functions. It is increasingly...
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Dementia Talks! Canada
https://braincanada.ca/fr/subventions-financées/dementia-talks-canadaPartners and Donors Alzheimer Society of Canada
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Des bourses pour accroître le bassin de chercheurs en santé cérébrale et cardiaque des femmes
https://braincanada.ca/fr/à-propos-de/nouvelles-mises-à-jour/des-bourses-pour-accroître-le-bassin-de-chercheurs-en-santé-cérébrale-et-cardiaque-des-femmesLa Fondation Brain Canada et Cœur + AVC ont le plaisir d’annoncer l’octroi de 15 bourses de fonctionnement afin de mieux comprendre en quoi les maladies du cerveau et du cœur touchent différemment les femmes des hommes. De concert avec Cœur + AVC, la Fondation Brain Canada accorde des bourses...
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Des chercheurs canadiens de premier plan à la tête de l'étude pionnière Canadian Proactive Cohort Study for People Living with MS (CanProCo)
https://braincanada.ca/fr/à-propos-de/nouvelles-mises-à-jour/d-éminents-chercheurs-canadiens-à-la-tête-de-l-étude-de-cohorte-proactive-canadienne-pour-les-personnes-vivant-avec-la-sclérose-en-plaques-canprocoUne équipe de chercheurs en SP de renommée mondiale, dirigée par le Dr Jiwon Oh, a été sélectionnée pour commencer à travailler sur la première cohorte canadienne visant à étudier la progression de la sclérose en plaques Toronto, ON - 6 décembre 2018 - La Société canadienne de la sclérose en plaques...