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Evaluation of electrical activity as a tumour suppressor in medulloblastoma
https://braincanada.ca/fr/subventions-financées/evaluation-of-electrical-activity-as-a-tumour-suppressor-in-medulloblastomaDr. Garzia works on a type of pediatric brain cancer called medulloblastoma. Project Overview Dr. Garzia works on a type of pediatric brain cancer called medulloblastoma. Kids affected by this tumor are either not cured or experience severe side effects due to the aggressive therapy. This proposal...
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Evaluation of Long-Axis Hippocampal Subfield Volumetry as a neuroimaging biomarker for Alzheimer’s disease
https://braincanada.ca/fr/subventions-financées/evaluation-of-long-axis-hippocampal-subfield-volumetry-as-a-neuroimaging-biomarker-for-alzheimer-s-diseaseThe hippocampus is the brain region which shows the most severe changes in patients with Alzheimer’s disease. Project Overview The hippocampus is the brain region which shows the most severe changes in patients with Alzheimer’s disease. Magnetic resonance imaging can be used to measure these...
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Evaluation of the Kids Write Network (KWN) intervention with children of severely ill parents: a qualitative and quantitative pilot study
https://braincanada.ca/fr/subventions-financées/evaluation-of-the-kids-write-network-kwn-intervention-with-children-of-severely-ill-parents-a-qualitative-and-quantitative-pilot-studyAdolescence represents a unique developmental window of the life cycle to adopt healthy behaviours that will support psychosocial adjustment and well-being during adolescence and adulthood (World Health Organization, 2001). Project Overview Adolescence represents a unique developmental window of...
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Evaluation of the role of EMMPRIN and MMP-9 in extracellular matrix degradation during ALS
https://braincanada.ca/fr/subventions-financées/evaluation-of-the-role-of-emmprin-and-mmp-9-in-extracellular-matrix-degradation-during-alsAmyotrophic Lateral Sclerosis (ALS) is a fatal disease that progressively destroys motor neurons, leading to paralysis and death, with no current cure. Project Overview Amyotrophic Lateral Sclerosis (ALS) is a fatal disease that progressively destroys motor neurons, leading to paralysis and death,...
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Examining the neurobiological substrates of antidepressant effects of psilocybin: a PET imaging study using SYNVEST1
https://braincanada.ca/fr/subventions-financées/examining-the-neurobiological-substrates-of-antidepressant-effects-of-psilocybin-a-pet-imaging-study-using-synvest1In Canada, over 1 million people have been diagnosed with bipolar disorder (BD) in their lifetime. Project Overview In Canada, over 1 million people have been diagnosed with bipolar disorder (BD) in their lifetime. BD is characterized by recurrent episodes of depression and (hypo)mania. Many people...
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Examining the role of KCC2 in maintaining the balance between excitation and inhibition in ALS
https://braincanada.ca/fr/subventions-financées/examining-the-role-of-kcc2-in-maintaining-the-balance-between-excitation-and-inhibition-in-alsEach muscle in the body receives electrical signals through motor neurons that will stimulate it to contract. Project Overview Each muscle in the body receives electrical signals through motor neurons that will stimulate it to contract. Other specialized neurons inhibit these signals, allowing...
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Examining vascular risk and menopausal age on women’s increased risk for AD
https://braincanada.ca/fr/subventions-financées/examining-vascular-risk-and-menopausal-age-on-women-s-increased-risk-for-adTwo-thirds of individuals suffering from Alzheimer’s disease are women. Project Overview Two-thirds of individuals suffering from Alzheimer’s disease are women. The reason for women’s increased risk of Alzheimer’s disease is unknown. Menopause occurs when a decline in a hormone called estrogen...
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Expanding CNDR as an Open Science, Multi-modal Data Platform
https://braincanada.ca/fr/subventions-financées/expanding-cndr-as-an-open-science-multi-modal-data-platformNeuromuscular diseases (NMDs) are rare conditions that affect nerves and muscles. Project Overview Neuromuscular diseases (NMDs) are rare conditions that affect nerves and muscles. These diseases can be complex and require significant healthcare resources, but because they are rare, there are many...
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Exploitation of a new pharmacological target for the development and validation of new anti-inflammatory drugs
https://braincanada.ca/fr/subventions-financées/exploitation-of-a-new-pharmacological-target-for-the-development-and-validation-of-new-anti-inflammatory-drugsNeuroinflammation has been implicated in a diverse array of degenerative conditions, ranging from Multiple Sclerosis to Alzheimer’s disease. Project Overview Neuroinflammation has been implicated in a diverse array of degenerative conditions, ranging from Multiple Sclerosis to Alzheimer’s ...
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Exploring a therapeutic approach to promote neuronal function for ALS
https://braincanada.ca/fr/subventions-financées/exploring-a-therapeutic-approach-to-promote-neuronal-function-for-alsAmyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are two devastating neurodegenerative diseases which have overlap in pathological features and the genetic basis. Project Overview Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are two devastating...
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