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Dissecting acetylcholine/glutamate co-transmission in the striatum: importance of individual neurotransmitter in addiction and movement disorders
https://braincanada.ca/fr/subventions-financées/dissecting-acetylcholine-glutamate-co-transmission-in-the-striatum-importance-of-individual-neurotransmitter-in-addiction-and-movement-disordersParkinson’s disease and addiction have tremendous human and economical costs for our society. Project Overview Parkinson’s disease and addiction have tremendous human and economical costs for our society. The secret to understand these pathologies lies in unravelling the functioning of a specific...
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Dissecting brain-wide functional circuits underlying social decision making by developing a naturalistic virtual reality platform of juvenile zebrafish
https://braincanada.ca/fr/subventions-financées/dissecting-brain-wide-functional-circuits-underlying-social-decision-making-by-developing-a-naturalistic-virtual-reality-platform-of-juvenile-zebrafishUnderstanding how the brain works when we make decisions during social interactions has been difficult for neuroscientists. Project Overview Understanding how the brain works when we make decisions during social interactions has been difficult for neuroscientists. This is because our brains process...
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Dissecting Inhibitory Circuit Control of Neurovascular Coupling
https://braincanada.ca/fr/subventions-financées/dissecting-inhibitory-circuit-control-of-neurovascular-couplingThe brain is one of the most energy-demanding organs in the body, yet it has no energy reserves. To function properly, it relies on a finely tuned process that increases local blood flow whenever neurons become active: a process known as neurovascular coupling (NVC). This link between brain activity...
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Dissecting the impact of biological sex and hormones on circadian microglial rhythms in chronic pain
https://braincanada.ca/fr/subventions-financées/dissecting-the-impact-of-biological-sex-and-hormones-on-circadian-microglial-rhythms-in-chronic-painPain doesn’t feel the same at every hour of the day. Many people notice their pain is worse at night or first thing in the morning, but we don’t yet understand why. Project Overview Pain doesn’t feel the same at every hour of the day. Many people notice their pain is worse at night or first thing...
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Dissecting the shared origins of schizophrenia and chronic cannabis use: A genomic investigation
https://braincanada.ca/fr/subventions-financées/dissecting-the-shared-origins-of-schizophrenia-and-chronic-cannabis-use-a-genomic-investigationRegular cannabis use is indisputably linked to schizophrenia. Project Overview Regular cannabis use is indisputably linked to schizophrenia. However, the causal nature and direction of this link is contentious and the biological mechanisms underpinning their relationship are poorly understood....
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Distinct neuro-immune interactions drive sex differences in chronic pain
https://braincanada.ca/fr/subventions-financées/distinct-neuro-immune-interactions-drive-sex-differences-in-chronic-painOne of the most important advances in our understanding of chronic pain over the last decade or so is the realization that neurons are not the only cells in the central nervous system participating in the processing of pain signals. Project Overview One of the most important advances in our...
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Distributed neural representations in confidence-guided reinforcement learning
https://braincanada.ca/fr/subventions-financées/distributed-neural-representations-in-confidence-guided-reinforcement-learningRodent models offer an opportunity to understand the computations performed in neural circuits at a much precise scale than using human neuroimaging. Project Overview Rodent models offer an opportunity to understand the computations performed in neural circuits at a much precise scale than using...
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Dix-neuf chercheurs noirs au Canada reçoivent une bourse inaugurale
https://braincanada.ca/fr/à-propos-de/nouvelles-mises-à-jour/dix-neuf-chercheurs-noirs-au-canada-reçoivent-une-bourse-inauguraleCes étudiants exceptionnels au doctorat et à la maîtrise sont engagés dans d'importantes recherches sur le cœur ou le cerveau. Heart & Stroke, en collaboration avec Brain Canada et l'Institut de la santé circulatoire et respiratoire des Instituts de recherche en santé du Canada (IRSC-ICRH), sont...
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Dix subventions d'un montant total d'un million de dollars sont accordées pour soutenir l'avenir de la recherche clinique sur les accidents vasculaires cérébraux
https://braincanada.ca/fr/à-propos-de/nouvelles-mises-à-jour/dix-subventions-d-un-montant-total-d-un-million-d-euros-accordées-pour-soutenir-l-avenir-de-la-recherche-clinique-sur-les-accidents-vasculaires-cérébrauxDe haut en bas, de gauche à droite : Dr Sean Dukelow, Dr Aravind Ganesh, Dr Raed Joundi, Dr Aristeidis Katsanos, Dr Ethan MacDonald, Dr Michelle Ploughman, Dr Alexandre Poppe, Dr Deborah Siegal, Dr Nishita Singh, Dr Luciano Sposato Le nouveau programme fournit un financement de démarrage vital...
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DNA damage driven motor disturbance in ALS: An ERVK integrase transgenic mouse model
https://braincanada.ca/fr/subventions-financées/dna-damage-driven-motor-disturbance-in-als-an-ervk-integrase-transgenic-mouse-modelEndogenous retrovirus-K (ERVK) is a genomic viral symbiont that contributes towards ALS neuropathology. Project Overview Endogenous retrovirus-K (ERVK) is a genomic viral symbiont that contributes towards ALS neuropathology. Our collaboration proposes to examine how ERVK integrase (IN) enzyme...