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Improving function and quality of life: rehabilitation for long-term care residents with moderate to severe dementia
https://braincanada.ca/fr/subventions-financées/improving-function-and-quality-of-life-rehabilitation-for-long-term-care-residents-with-moderate-to-severe-dementiaDevelop and disseminate a training program for rehabilitation providers working with long-term care residents with dementia. Project Overview Develop and disseminate a training program for rehabilitation providers working with long-term care residents with dementia. The training program will be...
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Improving Quality of Life in the Elderly by Standardizing Care for Neuropsychiatric Symptoms of Dementia
https://braincanada.ca/fr/subventions-financées/improving-quality-of-life-in-the-elderly-by-standardizing-care-for-neuropsychiatric-symptoms-of-dementiaAggression and agitation are common symptoms among patients with dementia. Project Overview Aggression and agitation are common symptoms among patients with dementia. These symptoms are the leading cause for hospitalization and admission to long-term care homes. Medication treatments that are...
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Improving the detection of brain injury in intimate partner violence patients
https://braincanada.ca/fr/subventions-financées/improving-the-detection-of-brain-injury-in-intimate-partner-violence-patientsThe recognition that mild traumatic brain injury (mTBI; i.e., concussion) has serious health effects has prompted an increase in research and clinical awareness, particularly in the context of sports and military. Project Overview The recognition that mild traumatic brain injury (mTBI; i.e.,...
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In-Home Dementia-Centred DIY Adaptations and Innovations
https://braincanada.ca/fr/subventions-financées/in-home-dementia-centred-diy-adaptations-and-innovationsThis project explores how people living with dementia and their caregivers create clever do-it-yourself (DIY) solutions to make everyday tasks at home easier and safer. Project Overview This project explores how people living with dementia and their caregivers create clever do-it-yourself (DIY)...
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In utero exposure to glucocorticoids in humans and an animal model: Epigenetic and transcriptional signatures
https://braincanada.ca/fr/subventions-financées/in-utero-exposure-to-glucocorticoids-in-humans-and-an-animal-model-epigenetic-and-transcriptional-signaturesDr. Sasaki research aims to (1) determine the mechanisms by which maternal synthetic glucocorticoids (sGC) modifies gene networks in a preclinical guinea pig model and (2) determine the mechanism by which a single maternal treatment of sGC modifies gene networks in human cord blood at term...
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In vitro and in vivo functional assessment of neuropsychiatric disease-related synaptic gene mutations
https://braincanada.ca/fr/subventions-financées/in-vitro-and-in-vivo-functional-assessment-of-neuropsychiatric-disease-related-synaptic-gene-mutationsDr. Xie’s research focuses on the functional assessment of neuropsychiatric disease related synaptic genes – MDGA1 and 2. MDGAs bind to critical neuron synaptic proteins – Neuroglin (NLGN), disrupting the binding between NLGN and Neurexin (NRXN), so suppressing synaptogenesis. Project Overview Dr....
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In-vivo CAR-T Therapy for Glioblastoma by Novel Non-Viral Gene Editing System
https://braincanada.ca/fr/subventions-financées/in-vivo-car-t-therapy-for-glioblastoma-by-novel-non-viral-gene-editing-systemCAR-T therapies have delivered promising results for certain hematological cancers but remain largely ineffective for solid tumours with failure nodes including complex and hostile tumor microenvironments and the lack of adapted technological tools. Project Overview Challenge CAR-T therapies have...
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In vivo Quantification of Synaptic Density in Youth With High-risk Cannabis Use: A Positron Emission Tomography Study With the Synaptic Vesicle Glycoprotein 2A Radiotracer [18F]SynVesT-1
https://braincanada.ca/fr/subventions-financées/in-vivo-quantification-of-synaptic-density-in-youth-with-high-risk-cannabis-use-a-positron-emission-tomography-study-with-the-synaptic-vesicle-glycoprotein-2a-radiotracer-18f-synvest-1Frequent heavy use of cannabis is increasingly common in young Canadians. Project Overview Canadian Consortium for the Investigation of Cannabinoids (CCIC) Neuroscience Fellowship in Cannabis and Cannabinoid Research Frequent heavy use of cannabis is increasingly common in young Canadians....
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Incidence, Trends, Determinants, and Prognosis of Post-Stroke Dementia (INTREPID): A 20-year registry and population-based cohort study
https://braincanada.ca/fr/subventions-financées/incidence-trends-determinants-and-prognosis-of-post-stroke-dementia-intrepid-a-20-year-registry-and-population-based-cohort-studyStroke is a common and disabling brain disorder which may have long-lasting effects. Project Overview Stroke is a common and disabling brain disorder which may have long-lasting effects. One of the most feared consequences is the development of cognitive decline and dementia after stroke....
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Inclusive Physical Activity for Kids: KidsAction and Indigenous Dance Programs in Northern BC
https://braincanada.ca/fr/subventions-financées/inclusive-physical-activity-for-kids-kidsaction-and-indigenous-dance-programs-in-northern-bcKidsAction is an evidence-informed coaching approach for children with disabilities. Project Overview KidsAction is an evidence-informed coaching approach for children with disabilities. We co-designed it with families, community groups and Indigenous partners to support children and families in...
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