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Individually Tailored Prediction of Treatments Response in Alzheimer’s Disease: 3 clinical trials validation
https://braincanada.ca/fr/subventions-financées/individually-tailored-prediction-of-treatments-response-in-alzheimer-s-disease-3-clinical-trials-validationLate-onset Alzheimer’s (late-AD) is a complex neurodegenerative condition with abnormalities in toxic protein accumulation, vascularization, inflammation, neuronal activity and cerebral atrophy. Project Overview Late-onset Alzheimer’s (late-AD) is a complex neurodegenerative condition with...
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Inferring computational principles in neural population recordings of evolutionarily-divergent species through artificial intelligence
https://braincanada.ca/fr/subventions-financées/inferring-computational-principles-in-neural-population-recordings-of-evolutionarily-divergent-species-through-artificial-intelligenceNeuroscientists seek to understand how the brain generates cognition and behavior. Project Overview Neuroscientists seek to understand how the brain generates cognition and behavior. A critical piece of this goal is fundamental research in model organisms that provide high degrees of experimental...
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Insulin resistance in the mesolimbic system, a novel hypothesis for depression associated with metabolic resistance from obesity.
https://braincanada.ca/fr/subventions-financées/insulin-resistance-in-the-mesolimbic-system-a-novel-hypothesis-for-depression-associated-with-metabolic-resistance-from-obesityDepression and anxiety are highly prevalent in people with obesity and type 2 diabetes. Project Overview Depression and anxiety are highly prevalent in people with obesity and type 2 diabetes. There are several theories of the cause of this association, however one commonality amongst these...
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Integrated Neurostimulation Platform for Neuropsychiatric Research
https://braincanada.ca/fr/subventions-financées/integrated-neurostimulation-platform-for-neuropsychiatric-researchThe offers the capacity to perform interleaved TMS/fMRI, a complex and demanding technique used to study brain function in neuropsychiatric disorders. Project Overview The offers the capacity to perform interleaved TMS/fMRI, a complex and demanding technique used to study brain function in...
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Integrative discovery of ion channels as drug targets in glioblastoma
https://braincanada.ca/fr/subventions-financées/integrative-discovery-of-ion-channels-as-drug-targets-in-glioblastomaIon channel (IC) proteins are known to be involved in different human diseases such as heart and brain disorders. Project Overview Ion channel (IC) proteins are known to be involved in different human diseases such as heart and brain disorders. There are many drugs that activate or inactivate ICs...
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Intensive Cancer Screening for Cryptogenic Stroke (INCOGNITO) Pilot Randomized Trial
https://braincanada.ca/fr/subventions-financées/intensive-cancer-screening-for-cryptogenic-stroke-incognito-pilot-randomized-trialThe first question people ask after suffering a stroke is: “Why?” Project Overview The first question people ask after suffering a stroke is: “Why?” A straightforward question, but for 4 in 10 stroke survivors, it’s also unanswerable. These are the people for whom routine tests reveal no...
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Interleukin-1 blockade along with hypothermia to prevent cerebral palsy arising from refractory neonatal asphyxia
https://braincanada.ca/fr/subventions-financées/interleukin-1-blockade-along-with-hypothermia-to-prevent-cerebral-palsy-arising-from-refractory-neonatal-asphyxiaNeonatal asphyxia and subsequent cerebral palsy (CP) is a severe pathology resulting from lack of oxygen and/or infection-inflammation. Project Overview Neonatal asphyxia and subsequent cerebral palsy (CP) is a severe pathology resulting from lack of oxygen and/or infection-inflammation. This...
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International Spinal Cord Injury Biobank (ISCIB): Promoting Global Spinal Cord Injury Research Through Human Biobanking
https://braincanada.ca/fr/subventions-financées/international-spinal-cord-injury-biobank-iscib-promoting-global-spinal-cord-injury-research-through-human-biobankingThe International Spinal Cord Injury Biobank (ISCIB) is a multi-user biorepository with the mission of accelerating therapeutic development in traumatic spinal cord injury (SCI) through improved biological understanding of human injury, and the vision of serving as a global research resource where...
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Interrogating the role of glial development in models of attention deficit hyperactivity disorder
https://braincanada.ca/fr/subventions-financées/interrogating-the-role-of-glial-development-in-models-of-attention-deficit-hyperactivity-disorderAttention-deficit hyperactivity disorder (ADHD) is the most common disorder that impacts development of the brain. Project Overview Attention-deficit hyperactivity disorder (ADHD) is the most common disorder that impacts development of the brain. ADHD is characterized by hyperactivity and...
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Intraoperative Identification of Residual Brain Tumour Using a Novel High-Resolution Ultrasound Endoscope and Integrated Neuronavigation System
https://braincanada.ca/fr/subventions-financées/intraoperative-identification-of-residual-brain-tumour-using-a-novel-high-resolution-ultrasound-endoscope-and-integrated-neuronavigation-system20,800 North Americans die from brain cancer each year. Project Overview 20,800 North Americans die from brain cancer each year. This project aims to improve patient outcomes by helping surgeons remove tumours with higher accuracy and less damage to healthy brain. When removing brain tumours,...