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Amyotrophic lateral sclerosis (ALS) is marked by dysfunction and degeneration of neuromuscular junctions (NMJ). Project Overview Amyotrophic lateral sclerosis (ALS) is marked by dysfunction and degeneration of neuromuscular junctions (NMJ). This can be one of the earliest pathological processes...

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterised by the loss of motor neurons and the atrophy of muscles. Project Overview Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterised by the loss of motor neurons and the atrophy of...

In this study, we. aim to do two things: 1) monitor the distribution of a-Syn in Parkinson’s disease (PD) context to understand the factors that can cause a-Syn to build-up in certain cells of the brain, called microglia. Project Overview In this study, we. aim to do two things: 1) monitor the...

Dr. Shmuel and his team are establishing a local platform which will support functional MRI (fMRI) in the alert non-human primate brain. Project Overview Dr. Shmuel and his team are establishing a local platform which will support functional MRI (fMRI) in the alert non-human primate brain. The...

Autism spectrum disorders (ASD) and schizophrenia (SZ) are two psychiatric conditions that affect approximately 2% of the general population. Genetic studies have identified mutations in hundreds of genes associated with ASD and SZ. Project Overview Autism spectrum disorders (ASD) and schizophrenia...

The project provides state of the art mouse brain imaging to researchers in Canada working on models of neurodevelopmental disorders. Project Overview The project provides state of the art mouse brain imaging to researchers in Canada working on models of neurodevelopmental disorders. The use of...

Neurodegenerative conditions such as Alzheimer’s and Parkinson’s disease profoundly affect aspects of cognition including memory Project Overview Neurodegenerative conditions such as Alzheimer’s and Parkinson’s disease profoundly affect aspects of cognition including memory, attention, decision...

A biological marker, or “biomarker” for short, is a measurable indicator associated with a disease state that helps determine risk, severity and response to therapy. Project Overview A biological marker, or “biomarker” for short, is a measurable indicator associated with a disease state that helps...

Parkinson’s disease (PD) is one of the most common neurodegenerative disorders in the world. Project Overview Parkinson’s disease (PD) is one of the most common neurodegenerative disorders in the world. PD can manifest and develop in a variety of ways for different patients, and it is currently not...

Autism spectrum disorder (ASD) affects approximately 1 in 70 children and is associated to a considerable burden for affected individuals, their families, and health care at large. Project Overview Autism spectrum disorder (ASD) affects approximately 1 in 70 children and is associated to a...