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As our brains age, they become vulnerable to diseases such as Alzheimer’s disease which can cause dementia. Project Overview As our brains age, they become vulnerable to diseases such as Alzheimer’s disease which can cause dementia. Dementia is defined as cognitive (i.e., thinking) problems that...

In Alzheimer s disease (AD), critical synaptic connections between neurons disintegrate and cells die. Project Overview In Alzheimer s disease (AD), critical synaptic connections between neurons disintegrate and cells die. The brains of individuals with AD accumulate plaques of a protein fragment...

Over 64% of older adults without neurocognitive disorders report forgetting the names of objects when speaking. Project Overview Over 64% of older adults without neurocognitive disorders report forgetting the names of objects when speaking. These difficulties are commonly dismissed as typical...

Neuropathic pain is a chronic pain disorder resulting from damage to the nerves. Project Overview Neuropathic pain is a chronic pain disorder resulting from damage to the nerves.  It may be due to cancer, diabetes or conditions like fibromyalgia. Neuropathic pain is often eased by antidepressant or...

In Alzheimer’s disease (AD), the accumulation of toxic Tau protein in neurons leads to the formation of neurofbillary tangles, cell death, and cognitive impairments. Project Overview In Alzheimer’s disease (AD), the accumulation of toxic Tau protein in neurons leads to the formation of...

For this project Dr. Sanjay Kalra and his team aims to improve on current techniques to use magnetic resonance imaging (MRI) as a readily available way to examine if a potential new treatment is working to slow down progression of ALS. Project Overview For this project Dr. Sanjay Kalra and his team...

ALS is a devastating neurological disease characterized by the progressive degeneration of motor neurons leading to paralysis and death. Project Overview ALS is a devastating neurological disease characterized by the progressive degeneration of motor neurons leading to paralysis and death....

Individuals with Alzheimer’s suffer severe memory loss over time, and eventually are completely dependent on caregivers. Project Overview Individuals with Alzheimer’s suffer severe memory loss over time, and eventually are completely dependent on caregivers. Age is a significant risk factor, and...

Communication between brain cells is essential for normal brain function. Project Overview Communication between brain cells is essential for normal brain function. Healthy brain cells are controlled through chemical messengers that stimulate or inhibit brain activity. Current theories indicate...

Dr David Stojdl’s lab has custom‑built an oncolytic virus biotherapy specifically for the treatment of the devastating brain cancer, glioblastoma multiforme (GBM). Project Overview Dr David Stojdl’s lab has custom‑built an oncolytic virus biotherapy specifically for the treatment of the devastating...