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Online detection and neuromodulation of replays during working memory in humans
https://braincanada.ca/fr/subventions-financées/online-detection-and-neuromodulation-of-replays-during-working-memory-in-humansWorking memory is our ability “keep in mind” information and manipulate it when it is not present in the environment. Project Overview Working memory is our ability “keep in mind” information and manipulate it when it is not present in the environment. It is central to many aspects of cognition,...
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Optimization of Prefrontal Theta-Burst Stimulation to Treat Depression: A Bench to First-in-Human Study
https://braincanada.ca/fr/subventions-financées/optimization-of-prefrontal-theta-burst-stimulation-to-treat-depression-a-bench-to-first-in-human-studyProject Overview Major depression is among the most common and most burdensome human diseases worldwide. While there are several existing treatments, overall current treatments are modest in their efficacy. Over the past few decades, there has been significant development in the field of...
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Optimizing nanodiscs to improve antisense oligonucleotide delivery in the treatment of Huntington disease.
https://braincanada.ca/fr/subventions-financées/optimizing-nanodiscs-to-improve-antisense-oligonucleotide-delivery-in-the-treatment-of-huntington-disease"Antisense oligonucleotides (ASOs) are synthetic single-stranded DNA/RNA that are useful in the targeting of mRNA sequences." Project Overview “Antisense oligonucleotides (ASOs) are synthetic single-stranded DNA/RNA that are useful in the targeting of mRNA sequences. Their versatility allows them...
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Ouvrir la voie et réaliser des percées
https://braincanada.ca/fr/à-propos-de/nouvelles-mises-à-jour/une-percée-faire-des-percéesBrain Canada a le plaisir d’annoncer la plus récente cohorte de bénéficiaires des subventions Momentum. Ce programme est conçu pour mettre à profit les travaux novateurs entrepris dans le cadre du programme Futurs leaders canadiens de la recherche sur le cerveau. Brain Canada annonce les 10...
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Ouvrir le monde
https://braincanada.ca/fr/à-propos-de/nouvelles-mises-à-jour/ouvrir-le-mondeÀ l'âge de 25 ans, le Dr Monica Seger a reçu une bourse pour effectuer un stage postdoctoral aux Pays-Bas. Cette expérience a changé la trajectoire de sa vie et de ses recherches. En tant que jeune neuroendocrinologue, Monica a énormément bénéficié de la collaboration avec des scientifiques d'une...
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Parent-therapist partnership to provide early, intensive exercise to enhance walking outcomes in children with perinatal stroke
https://braincanada.ca/fr/subventions-financées/parent-therapist-partnership-to-provide-early-intensive-exercise-to-enhance-walking-outcomes-in-children-with-perinatal-strokePerinatal (around birth) stroke is devastating, because the effects are life-long. Project Overview Perinatal (around birth) stroke is devastating, because the effects are life-long. Current treatments to improve walking are limited, and largely passive, such as stretching, bracing, botulinum toxin...
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Partners and Donors Alzheimer Society of Canada
https://braincanada.ca/fr/subventions-financées/partners-and-donors-alzheimer-society-of-canadaPartners and Donors Alzheimer Society of Canada Alzheimer’s disease is a common form of memory loss and confusion affecting older adults. Despite many years of study, we still don’t have a cure for this disease. Project Overview Alzheimer’s disease is a common form of memory loss and confusion...
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Pathogenic Mechanism of C9orf72 haploinsufficiency in ALS/FTLD: a road to therapeutic discovery
https://braincanada.ca/fr/subventions-financées/pathogenic-mechanism-of-c9orf72-haploinsufficiency-in-als-ftld-a-road-to-therapeutic-discoveryIn this Hudson project, the team led by Dr. Robertson will pursue a comprehensive understanding of the normal functions of C9ORF72 and provide a better determination of whether loss of these functions via mutation may cause or contribute to ALS. Project Overview In this Hudson project, the team led...
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Pathogenic mechanisms of C9ORF72 repeat expansion in ALS and development of therapeutics
https://braincanada.ca/fr/subventions-financées/pathogenic-mechanisms-of-c9orf72-repeat-expansion-in-als-and-development-of-therapeuticsDr. Patten started his research career as a PhD student at the University of Alberta under the supervision of Dr. Declan Ali in 2004. Project Overview Dr. Patten started his research career as a PhD student at the University of Alberta under the supervision of Dr. Declan Ali in 2004. There he...
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Patient-reported outcome measures for social robots in dementia care
https://braincanada.ca/fr/subventions-financées/patient-reported-outcome-measures-for-social-robots-in-dementia-careImproving independence and quality of life for persons living with dementia (PLWD) and their care partners can be realized by complementing human care with robotic assistive technologies. Project Overview Improving independence and quality of life for persons living with dementia (PLWD) and their...