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Testing white matter pathway’s influence on neural communication: A combined structural and functional neuroimaging study
https://braincanada.ca/fr/subventions-financées/testing-white-matter-pathway-s-influence-on-neural-communication-a-combined-structural-and-functional-neuroimaging-studyMs. Decker will test the hypothesis that myelin damage impairs episodic memory by disrupting neural communication between two memory relevant brain regions, namely, the hippocampus and prefrontal cortex. Accordingly, she will examine neural synchrony, (a measure of neural communication), during an...
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The 5kEEG project: Large-scale Electrophysiological Investigation of Autism and Neurodevelopmental Disorders
https://braincanada.ca/fr/subventions-financées/the-5keeg-project-large-scale-electrophysiological-investigation-of-autism-and-neurodevelopmental-disordersThe 5kEEG project is a pioneering study that aims to improve our understanding of autism and neurodevelopmental disorders by investigating brain activity. Project Overview The 5kEEG project is a pioneering study that aims to improve our understanding of autism and neurodevelopmental disorders by...
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The Aging Brain: Circadian, Transcriptomic, and Epigenomic Dimensions
https://braincanada.ca/fr/subventions-financées/the-aging-brain-circadian-transcriptomic-and-epigenomic-dimensionsOne of the most important questions of biomedical research is “why do we ail as we age?”. Project Overview One of the most important questions of biomedical research is “why do we ail as we age?”. This may be in part due to a breakdown of the body’s circadian rhythm – the physiological process that...
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The application of 3D models to assess the role of microglia in neurodegenerative disorders
https://braincanada.ca/fr/subventions-financées/the-application-of-3d-models-to-assess-the-role-of-microglia-in-neurodegenerative-disordersChallenge: Alzheimer’s disease (AD) is characterized by a decline in cognitive function, yet it is now widely acknowledged that as the disease advances, dopaminergic neurons in the midbrain become particularly vulnerable, leading to non-cognitive symptoms such as motor dysfunction. Project...
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The Applied Organoid Core (ApOC): a organoid production platform for modelling human brain development and disease
https://braincanada.ca/fr/subventions-financées/the-applied-organoid-core-apoc-a-organoid-production-platform-for-modelling-human-brain-development-and-diseaseCurrent preclinical models to address neurological disorders fail to accurately portray human physiology. Project Overview Current preclinical models to address neurological disorders fail to accurately portray human physiology. First, traditional tissue culture in which neuronal cells are grown in...
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The Automated Monitoring of Gait as a Predictor of Fall Risk
https://braincanada.ca/fr/subventions-financées/the-automated-monitoring-of-gait-as-a-predictor-of-fall-riskPeople with dementia are at a high risk for falls which are a leading cause of injury and can contribute to loss of independence and quality of life. Project Overview People with dementia are at a high risk for falls which are a leading cause of injury and can contribute to loss of independence and...
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The Brain Single Cell Initiative
https://braincanada.ca/fr/subventions-financées/the-brain-single-cell-initiativeThe recent breakthrough technology of single-cell genomics has vastly improved our capacity to understand how the trillions of cells in our body develop and work together to make us human. Project Overview The recent breakthrough technology of single-cell genomics has vastly improved our capacity...
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The Canadian Alzheimer’s Prevention Data Repository and Sharing Platform: accelerating Alzheimer’s disease research and treatment in Canada and beyond
https://braincanada.ca/fr/subventions-financées/the-canadian-alzheimer-s-prevention-data-repository-and-sharing-platform-accelerating-alzheimer-s-disease-research-and-treatment-in-canada-and-beyondBy the time a person receives a diagnosis of Alzheimer’s disease (AD) dementia, brain atrophy is such that memory impairments are irreversible. Project Overview By the time a person receives a diagnosis of Alzheimer’s disease (AD) dementia, brain atrophy is such that memory impairments are...
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The Canadian Neonatal Brain Platform
https://braincanada.ca/fr/subventions-financées/the-canadian-neonatal-brain-platformThe neonatal brain is exquisitely vulnerable to the biological consequences of prematurity, birth asphyxia and congenital heart defects. Project Overview The neonatal brain is exquisitely vulnerable to the biological consequences of prematurity, birth asphyxia and congenital heart defects. Brain...
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The CAnadian Network for Psychedelic-Assisted Cancer Therapy (CAN-PACT): Building a Research, Practice and Policy Foundation
https://braincanada.ca/fr/subventions-financées/the-canadian-network-for-psychedelic-assisted-cancer-therapy-can-pact-building-a-research-practice-and-policy-foundationA new national initiative funded by the Canadian Cancer Society, the Canadian Network for Psychedelic-Assisted Cancer Therapy (CAN-PACT), is bringing together researchers, clinicians, policymakers, and people living with advanced cancer to explore the potential of psychedelic-assisted therapy as a...