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Les subventions relatives à l’application des connaissances font passer des recherches révolutionnaires sur les troubles neurocognitifs à l’état d’impact
https://braincanada.ca/fr/à-propos-de/nouvelles-mises-à-jour/les-subventions-relatives-à-l-application-des-connaissances-font-passer-des-recherches-révolutionnaires-sur-les-troubles-neurocognitifs-à-l-état-d-impactLa Société Alzheimer du Canada et la Fondation Brain Canada annoncent les récipiendaires des subventions d’accélération de l’ATC PHOTO : De gauche à droite : Caitlin McArthur, Laura Middleton, Gary Naglie, Marie Savundranayagam et Eric Smith. La Société Alzheimer du Canada et la Fondation Brain...
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Leveraging proximity interactomics to identify therapeutically targetable RNA-binding proteins in G4C2 repeat-driven ALS
https://braincanada.ca/fr/subventions-financées/leveraging-proximity-interactomics-to-identify-therapeutically-targetable-rna-binding-proteins-in-g4c2-repeat-driven-alsAmyotrophic lateral sclerosis (ALS) is a progressive disease that causes loss of control over muscles and leads to death quickly after diagnosis. Project Overview Amyotrophic lateral sclerosis (ALS) is a progressive disease that causes loss of control over muscles and leads to death quickly after...
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Lifespan Brain Health Trajectories in Congenital Heart Disease: the role of sex & gender
https://braincanada.ca/fr/subventions-financées/lifespan-brain-health-trajectories-in-congenital-heart-disease-the-role-of-sex-genderCongenital heart disease (“CHD”) refers to problems with heart structure and function that begin at birth. Project Overview Congenital heart disease (“CHD”) refers to problems with heart structure and function that begin at birth. People with CHD are now living longer than ever before because of...
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Linking reduced cell-specific inhibition to abnormal brain activity in chronic stress
https://braincanada.ca/fr/subventions-financées/linking-reduced-cell-specific-inhibition-to-abnormal-brain-activity-in-chronic-stressDepression is a leading cause of disability, with a large proportion of treatment-resistant patients. Recent studies have implicated reduced brain inhibition in human depression from a specific neuron type (SST), and new pharmacology boosting this reduced inhibition led to antidepressant and...
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Lire le dernier numéro du magazine Mind Over Matter de l'IHAB
https://braincanada.ca/fr/à-propos-de/nouvelles-mises-à-jour/lisez-le-dernier-numéro-du-magazine-mind-over-matter-de-l-omcLisez le dernier numéro du magazine Mind Over Matter, publié par le Women's Brain Health Initiative, en partenariat avec Brain Canada. Ce numéro comprend un article inspirant sur la Dre Nathalie Bier, chercheuse financée par Brain Canada, et sur ses travaux visant à aider les personnes atteintes de...
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Locally produced brain insulin in memory and Alzheimer’s disease: A multi-disciplinary approach to a key question
https://braincanada.ca/fr/subventions-financées/locally-produced-brain-insulin-in-memory-and-alzheimer-s-disease-a-multi-disciplinary-approach-to-a-key-questionOne percent of Alzheimer’s disease is the early-onset type that runs in families. Project Overview One percent of Alzheimer’s disease is the early-onset type that runs in families. Extensive studies of these ultra-rare forms of Alzheimer’s disease have revealed the genes that cause them. On the...
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Long-term effects of inhaled cannabis delivery during pregnancy on adolescent social behaviour and adult emotional behaviour in male and female rats
https://braincanada.ca/fr/subventions-financées/long-term-effects-of-inhaled-cannabis-delivery-during-pregnancy-on-adolescent-social-behaviour-and-adult-emotional-behaviour-in-male-and-female-ratsRoughly 10-20% of people self-report use of cannabis during pregnancy. Project Overview Canadian Consortium for the Investigation of Cannabinoids (CCIC) Neuroscience Fellowship in Cannabis and Cannabinoid Research Roughly 10-20% of people self-report use of cannabis during pregnancy. Human studies...
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Longitudinal Neurocognitive Trajectories in Perinatal Arterial Ischemic Stroke
https://braincanada.ca/fr/subventions-financées/longitudinal-neurocognitive-trajectories-in-perinatal-arterial-ischemic-strokeThe highest lifetime risk of stroke is the week surrounding birth, with perinatal arterial ischemic stroke (AIS) the most common stroke subtype during this period. The highest lifetime risk of stroke is the week surrounding birth, with perinatal arterial ischemic stroke (AIS) the most common stroke...
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Longitudinal single-cell multiomic profiling toward elucidating the differential roles of sex and hormones on the molecular programming of the brain
https://braincanada.ca/fr/subventions-financées/longitudinal-single-cell-multiomic-profiling-toward-elucidating-the-differential-roles-of-sex-and-hormones-on-the-molecular-programming-of-the-brainThere are many neurological and neuropsychiatric diseases that affect men and women differently, and the reasons for this are not well understood. Project Overview There are many neurological and neuropsychiatric diseases that affect men and women differently, and the reasons for this are not well...
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Loss of C9orf72 disrupts nucleoporins and contributes to TDP-43 mislocalization
https://braincanada.ca/fr/subventions-financées/loss-of-c9orf72-disrupts-nucleoporins-and-contributes-to-tdp-43-mislocalizationSubcellular compartmentalization between the nucleus and cytoplasm is primarily governed by two systems; 1) active nucleocytoplasmic transport (NCT) regulated by Ran-GTPase and involving nuclear transport receptors such as Importin β-1, and 2) macromolecular nuclear pore complexes (NPCs) Project...
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