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Huntington disease (HD) is an inherited disorder that causes brain cells to die and impacts approximately 1 in 7000 Canadians. Project Overview Huntington disease (HD) is an inherited disorder that causes brain cells to die and impacts approximately 1 in 7000 Canadians. A person with HD experiences...

One of the largest predictors of mental illness is childhood emotional and behavioural problems (EBP, e.g., aggression, anxiety, depression), which occur in 12-26% of children under age 6 years. Project Overview One of the largest predictors of mental illness is childhood emotional and behavioural...

En 2016, Yasser Iturria-Medina, Ph.D., et son superviseur postdoctoral de l’époque, Alan Evans, Ph.D., ont publié des résultats qui ont tranquillement contribué à modifier la façon dont les scientifiques envisagent la maladie d’Alzheimer. Aujourd’hui, ces travaux ont donné lieu à plusieurs brevets...

Complex research questions in neurology are often most effectively addressed by monitoring brain structure and function in human patients and live animals in experimental disease models. Project Overview Complex research questions in neurology are often most effectively addressed by monitoring...

Medulloblastoma isthe most common brain cancer in children. Project Overview Medulloblastoma isthe most common brain cancer in children. The current treatment for it includestoxic chemotherapy drugs which leadsto severe long-term side effectslike cognitive impairment. Still, the treatment failsfor...

For decades, brain function was thought to follow a simple rule: each brain region performs a single function. It is now understood that the brain operates as a complex network, where different regions work together. The cortex (gray matter) forms the outer layer of the brain and is responsible for...

The brain is more than the sum of its parts. Project Overview The brain is more than the sum of its parts. Truly understanding the brain’s most intricate properties requires both a list of its individual parts, that is a census of the types of neurons it contains, and a map of how these parts are...

Isolated REM sleep behavior disorder (iRBD) is a sleep condition where people physically act out dreams because the normal muscle “paralysis” of REM sleep is lost. It is confirmed by an overnight sleep study with video monitoring. iRBD matters because it is one of the strongest known early warning...

The brain is an incredibly complex organ. Much of the brain’s complexity may be attributed to the circuitry that resides within. Project Overview The brain is an incredibly complex organ. Much of the brain’s complexity may be attributed to the circuitry that resides within. Synaptic connections are...

Maternal depression, particularly during pregnancy, has been well established as a risk factor for child socio-emotional problems. Project Overview Maternal depression, particularly during pregnancy, has been well established as a risk factor for child socio-emotional problems. However, the impact...