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Understanding addiction through zebrafish: unveiling new solutions
https://braincanada.ca/fr/subventions-financées/understanding-addiction-through-zebrafish-unveiling-new-solutionsAddiction is a massive issue that spans generations and cultures. Project Overview Addiction is a massive issue that spans generations and cultures. Understanding and learning to help those suffering from addiction should continue to be a high- priority topic. Whether it’s looking to the past for...
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Understanding brain development and maintenance via spatial transcriptomics
https://braincanada.ca/fr/subventions-financées/understanding-brain-development-and-maintenance-via-spatial-transcriptomicsWe identified changes in the gene called IRF2BPL (Interferon Regulatory Factor 2 Binding Protein Like) as the cause of a severe brain disorder in children called NEDAMSS (Neurodevelopmental disorder with abnormal movements, loss of speech and seizures). Project Overview We identified changes in the...
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Understanding cerebral blood flow control in humans after cannabis use
https://braincanada.ca/fr/subventions-financées/understanding-cerebral-blood-flow-control-in-humans-after-cannabis-useCannabis is one of the most commonly used recreational substances in Canada, yet its effects on brain blood flow remain poorly understood. Project Overview Cannabis is one of the most commonly used recreational substances in Canada, yet its effects on brain blood flow remain poorly understood....
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Understanding how deviations in postnatal hippocampal neurogenesis and circuit activity contribute to bipolar disorder with patient-derived pluripotent stem cells
https://braincanada.ca/fr/subventions-financées/understanding-how-deviations-in-postnatal-hippocampal-neurogenesis-and-circuit-activity-contribute-to-bipolar-disorder-with-patient-derived-pluripotent-stem-cellsThe brain is vulnerable to many disorders that can strike at every stage of life. Project Overview The brain is vulnerable to many disorders that can strike at every stage of life. Bipolar disorder (BD) is a chronic and disabling neuropsychiatric condition that affects 1 in 50 Canadian adults. Like...
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Understanding how pain varies and its effect on well-being in children and youth with cerebral palsy: A mixed methods study
https://braincanada.ca/fr/subventions-financées/understanding-how-pain-varies-and-its-effect-on-well-being-in-children-and-youth-with-cerebral-palsy-a-mixed-methods-studyMs. Shearer’s study is the first to address the knowledge gap related to multiple short-term pain fluctuations, the temporal association of pain trajectories on well-being, and the experiential assessment and data triangulation of pain trajectories and their impact, all using self-reported data....
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Understanding Porphyromonas gingivalis Infection in Alzheimer’s Disease
https://braincanada.ca/fr/subventions-financées/understanding-porphyromonas-gingivalis-infection-in-alzheimer-s-diseasePeriodontitis, a chronic oral inflammatory disease-causing tissue damage, bone deterioration and tooth loss, has been linked to Alzheimer’s disease. Project Overview Periodontitis, a chronic oral inflammatory disease-causing tissue damage, bone deterioration and tooth loss, has been linked to...
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Understanding stress to improve mental health
https://braincanada.ca/fr/subventions-financées/understanding-stress-to-improve-mental-healthRecent estimates indicate that 1 in 5 Canadians are affected annually by mood, anxiety and other mental illnesses. Project Overview Recent estimates indicate that 1 in 5 Canadians are affected annually by mood, anxiety and other mental illnesses. These issues are exacerbated by stress. This is...
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Understanding the contribution of non-neuronal brain cells in cognition and behaviour
https://braincanada.ca/fr/subventions-financées/understanding-the-contribution-of-non-neuronal-brain-cells-in-cognition-and-behaviourThe increasing prevalence of anxio-depressive disorders worldwide suggests that current therapeutic strategies are insufficient in tackling this global health concern. Project Overview The increasing prevalence of anxio-depressive disorders worldwide suggests that current therapeutic strategies are...
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Understanding the interactions between hypertension and HD
https://braincanada.ca/fr/subventions-financées/understanding-the-interactions-between-hypertension-and-hdPartners and Donors Huntington Society of Canada
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Understanding why some breast cancers spread to the brain
https://braincanada.ca/fr/subventions-financées/understanding-why-some-breast-cancers-spread-to-the-brainRober Abdo is investigating molecular changes in breast cancer cells which enable them to spread to the brain. Project Overview Rober Abdo is investigating molecular changes in breast cancer cells which enable them to spread to the brain. Although new treatments and earlier diagnosis have improved...