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835 résultats trouvés

Profiling Cortical Excitability in ALS Using Threshold Tracking Transcranial Magnetic Stimulation and Multimodal Biomarkers

Rationale: Cortical hyperexcitability has been identified to be a potential driver of ALS pathology leading to excitotoxicity and degeneration of upper motor neurons (UMNs)in the primary motor cortex (M1) and the subsequent degeneration of lower motor neurons (LMNs) in the spinal cord.


Domaine de recherche
Neurodégénérescence
Province
Ontario
DATE DE DÉBUT
2023

Defective protein translation: a causative pathway in ALS?

Almost all amyotrophic lateral sclerosis (ALS) is accompanied by neuronal cytoplasmic aggregates of TAR DNA-binding protein-43 (TDP-43).


Domaine de recherche
Neurodégénérescence
Province
Colombie-Britannique
DATE DE DÉBUT
2023

Development of a shared decision-making aid for bulbar symptom management in ALS

Bulbar disease, which affects speech and swallowing functions, is considered to be one of the most debilitating aspects of ALS by patients.


Domaine de recherche
Neurodégénérescence
Province
Ontario
DATE DE DÉBUT
2023

Examining vascular risk and menopausal age on women’s increased risk for AD

Two-thirds of individuals suffering from Alzheimer’s disease are women.


TYPE DE SUBVENTION
Subventions pour le renforcement des capacités
Domaine de recherche
Neurodégénérescence
Province
Ontario
DATE DE DÉBUT
2023

Resetting Microglia Activation in Offspring Exposed to Maternal High-Fat Diet

Nutrition and diet are factors in life that contribute drastically to a person’s brain health, and overall quality of life, and high-fat diets can be considered a cause of many harmful physical and cognitive conditions.


TYPE DE SUBVENTION
Subventions pour le renforcement des capacités
Domaine de recherche
Système nerveux central
Concours
Prix du personnel de maîtrise pour les boursiers noirs
Province
Ontario
DATE DE DÉBUT
2023

How brainstem microstructural integrity relates to decision-making biases in Alzheimer’s Disease

The exploration versus exploitation (E&E) decision making trade-off is something we experience every day.


TYPE DE SUBVENTION
Subventions pour le renforcement des capacités
Domaine de recherche
Neurodégénérescence
Concours
Prix du personnel de maîtrise pour les boursiers noirs
Province
Ontario
DATE DE DÉBUT
2023

Self-disclosure about dementia on social media: evidence-informed guidance

Individuals who engage on social media often disclose a personal dementia diagnosis or identify as a caregiver, yet little is known about the impact of that disclosure.


TYPE DE SUBVENTION
Subventions pour le renforcement des capacités
Domaine de recherche
Neurodégénérescence
Province
Colombie-Britannique
DATE DE DÉBUT
2023

Effects of music listening on motor performance in people living with stroke

This study will investigate whether listening to music can help a stroke survivor improve their ability to move.


TYPE DE SUBVENTION
Subventions pour le renforcement des capacités
Domaine de recherche
Blessures
Concours
Bourses de doctorat pour les chercheurs noirs
Province
Ontario
DATE DE DÉBUT
2023

Patient-reported outcome measures for social robots in dementia care

Improving independence and quality of life for persons living with dementia (PLWD) and their care partners can be realized by complementing human care with robotic assistive technologies.


TYPE DE SUBVENTION
Subventions d'équipe
Domaine de recherche
Neurodégénérescence
Province
Colombie-Britannique
DATE DE DÉBUT
2023

Mind Over Matter Magazine (Volume 16)


TYPE DE SUBVENTION
Subventions pour l'application des connaissances
Domaine de recherche
Traduction des connaissances
Concours
Autres
Province
Ontario
DATE DE DÉBUT
2023