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Profiling Cortical Excitability in ALS Using Threshold Tracking Transcranial Magnetic Stimulation and Multimodal Biomarkers

Rationale: Cortical hyperexcitability has been identified to be a potential driver of ALS pathology leading to excitotoxicity and degeneration of upper motor neurons (UMNs)in the primary motor cortex (M1) and the subsequent degeneration of lower motor neurons (LMNs) in the spinal cord.

Project ongoing See Project & Researchers
Area of Research
Neurodegeneration
Competition
2023 ALS Canada - Brain Canada Trainee Program
Province
Ontario
Start Date
2023