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In ALS, the disease is characterized by degeneration of motor neurons and an inability of the brain to signal the muscles to move, resulting in paralysis. Project Overview In ALS, the disease is characterized by degeneration of motor neurons and an inability of the brain to signal the muscles to...

In 2019, a team of scientists led by co-recipient Dr. Sali Farhan discovered a new genetic cause of ALS called DNAJC7. Project Overview In 2019, a team of scientists led by co-recipient Dr. Sali Farhan discovered a new genetic cause of ALS called DNAJC7. Subsequent work revealed that mutations in...

Does SARS-CoV-2 infection increase cognitive decline via myelin loss in older individuals? Project Overview Does SARS-CoV-2 infection increase cognitive decline via myelin loss in older individuals? Background: One in 4 persons infected with SARS-CoV-2 (the COVID-19 virus) shows cognitive decline....

Indigenous health research is an emerging discipline and Inuit traditional ways of knowing are not fully articulated in health research practice, due to the impacts of colonization. Project Overview Indigenous health research is an emerging discipline and Inuit traditional ways of knowing are not...

Most people living with dementia (PLWD) live in community supported by informal care partners. Project Overview Most people living with dementia (PLWD) live in community supported by informal care partners. Continued access to community is a human right, and linked to better physical, mental, and...

Why do people feel pain differently, and why does it last longer for some even after healing? Project Overview Why do people feel pain differently, and why does it last longer for some even after healing? Despite decades of research in the neuroscience of pain, our understanding of how pain is...

How do we seamlessly transition between reading a novel and reminiscing our last vacation before the pandemic? Project Overview How do we seamlessly transition between reading a novel and reminiscing our last vacation before the pandemic? The ability to flexibly shift our attention between the...

In Canada, 1 in 20 people live with depression. Substantial efforts have been made over the years to develop new treatments to enhance therapeutic options. Project Overview In Canada, 1 in 20 people live with depression. Substantial efforts have been made over the years to develop new treatments to...

Melanoma brain metastases (MBMs) are a serious issue affecting up to half of all patients with stage IV melanoma, typically leading to a poor outlook. Project Overview Melanoma brain metastases (MBMs) are a serious issue affecting up to half of all patients with stage IV melanoma, typically leading...

Noninvasive brain stimulation is gaining acceptance as an alternate therapy for an increasing number of disorders, including major depression, schizophrenia, stroke and Parkinson’s disease. Project Overview Noninvasive brain stimulation is gaining acceptance as an alternate therapy for an...