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Impaired Neuromuscular Junction Connectivity in Amyotrophic Lateral Sclerosis
https://braincanada.ca/fr/subventions-financées/impaired-neuromuscular-junction-connectivity-in-amyotrophic-lateral-sclerosisMany scientists believe that one of the earliest abnormalities in ALS is dysfunction at the place where motor neurons connect to muscle, known as the neuromuscular junction (NMJ). Project Overview Many scientists believe that one of the earliest abnormalities in ALS is dysfunction at the place...
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Impaired orexin activity as a mediator of isolation-induced social anxiety
https://braincanada.ca/fr/subventions-financées/impaired-orexin-activity-as-a-mediator-of-isolation-induced-social-anxietyWe live in a world profoundly shaped by social behaviours involving interactions and communications between conspecifics of a given species. Project Overview We live in a world profoundly shaped by social behaviours involving interactions and communications between conspecifics of a given species....
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Impaired translational regulation of brain development in autism spectrum disorders
https://braincanada.ca/fr/subventions-financées/impaired-translational-regulation-of-brain-development-in-autism-spectrum-disordersAutism spectrum disorders (ASDs) are a group of complex neurodevelopmental disorders with distinguished early emerging behavioral disruptions (speech impairments, social communication, repetitive behaviors) and a rising rate of diagnosis to an estimated 1 in 68 children. Project Overview Autism...
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Implementation of a Clinical Pathway for Acute Care of Pediatric Concussion: Uptake, Outcomes, and Health Care Impacts
https://braincanada.ca/fr/subventions-financées/implementation-of-a-clinical-pathway-for-acute-care-of-pediatric-concussion-uptake-outcomes-and-health-care-impactsEach year, 1-2 million children in North America suffer a concussion. Project Overview Each year, 1-2 million children in North America suffer a concussion. Guidelines exist to manage the care of concussion in children but have not been implemented consistently. As a result, clinical practice...
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Improving function and quality of life: rehabilitation for long-term care residents with moderate to severe dementia
https://braincanada.ca/fr/subventions-financées/improving-function-and-quality-of-life-rehabilitation-for-long-term-care-residents-with-moderate-to-severe-dementiaDevelop and disseminate a training program for rehabilitation providers working with long-term care residents with dementia. Project Overview Develop and disseminate a training program for rehabilitation providers working with long-term care residents with dementia. The training program will be...
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Improving Quality of Life in the Elderly by Standardizing Care for Neuropsychiatric Symptoms of Dementia
https://braincanada.ca/fr/subventions-financées/improving-quality-of-life-in-the-elderly-by-standardizing-care-for-neuropsychiatric-symptoms-of-dementiaAggression and agitation are common symptoms among patients with dementia. Project Overview Aggression and agitation are common symptoms among patients with dementia. These symptoms are the leading cause for hospitalization and admission to long-term care homes. Medication treatments that are...
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Improving the detection of brain injury in intimate partner violence patients
https://braincanada.ca/fr/subventions-financées/improving-the-detection-of-brain-injury-in-intimate-partner-violence-patientsThe recognition that mild traumatic brain injury (mTBI; i.e., concussion) has serious health effects has prompted an increase in research and clinical awareness, particularly in the context of sports and military. Project Overview The recognition that mild traumatic brain injury (mTBI; i.e.,...
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In-Home Dementia-Centred DIY Adaptations and Innovations
https://braincanada.ca/fr/subventions-financées/in-home-dementia-centred-diy-adaptations-and-innovationsThis project explores how people living with dementia and their caregivers create clever do-it-yourself (DIY) solutions to make everyday tasks at home easier and safer. Project Overview This project explores how people living with dementia and their caregivers create clever do-it-yourself (DIY)...
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In Memoriam - Glenda MacQueen, membre du conseil d'administration de Brain Canada
https://braincanada.ca/fr/à-propos-de/nouvelles-mises-à-jour/in-memoriam-glenda-macqueen-membre-du-conseil-d-administration-de-brain-canadaLe Conseil d'administration, la direction et le personnel de Brain Canada sont attristés d'apprendre le décès du Dr Glenda MacQueen. Le Dr MacQueen était une championne de la science du cerveau au Canada et a apporté rigueur et perspicacité au Conseil d'administration de Brain Canada. Elle nous...
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In utero exposure to glucocorticoids in humans and an animal model: Epigenetic and transcriptional signatures
https://braincanada.ca/fr/subventions-financées/in-utero-exposure-to-glucocorticoids-in-humans-and-an-animal-model-epigenetic-and-transcriptional-signaturesDr. Sasaki research aims to (1) determine the mechanisms by which maternal synthetic glucocorticoids (sGC) modifies gene networks in a preclinical guinea pig model and (2) determine the mechanism by which a single maternal treatment of sGC modifies gene networks in human cord blood at term...