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Multiple Sclerosis (MS) is a disease where the immune system attacks the brain and spinal cord. Project Overview Multiple Sclerosis (MS) is a disease where the immune system attacks the brain and spinal cord. The resulting disability can range from vision loss in one eye or complete paralysis....

Recent studies have shown that damage to the small blood vessels in the brain (cerebrovascular disease) may increase the risk for Alzheimer’s. Project Overview Recent studies have shown that damage to the small blood vessels in the brain (cerebrovascular disease) may increase the risk for...

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by the loss of upper and lower motor neurons (MNs). Project Overview Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by the loss of upper and lower motor neurons (MNs). Symptoms include...

The rapid formation of new memories and the recall of old memories to inform decisions is essential for human cognition, but the underlying neural mechanisms remain poorly understood. Project Overview The rapid formation of new memories and the recall of old memories to inform decisions is...

Neurons are cells with long extensions that send information from one part of the nervous system to another. Project Overview Neurons are cells with long extensions that send information from one part of the nervous system to another. Two types of neural extensions exist: the dendrites, which...

The demonstration that mature somatic cells can be converted to new, heterologous cell types, now termed “cellular reprogramming”, led to the 2012 Nobel Prize in Physiology or Medicine, and sparked an explosion of studies investigating the therapeutic potential of such an approach. Project...

Amblyopia (commonly known as “lazy eye”) is a common developmental visual disorder, caused by eye misalignment, unequal refractive error between two eyes, or visual deprivation, with lifelong consequences on learning and academic achievements that we do not fully understand. It affects 4.7% of...

Spinal cord injury (SCI) is a devastating medical condition that forever changes the trajectory of life. Project Overview Spinal cord injury (SCI) is a devastating medical condition that forever changes the trajectory of life. It is also costly to the health care system, similar to traumatic brain...

The emerging consensus that the brain functions as a single, complex system has led to the popularity of a network approach to studying brain function. Project Overview The emerging consensus that the brain functions as a single, complex system has led to the popularity of a network approach to...

Deregulation of brain cell metabolism is commonly observed in low-grade brain cancers. Project Overview Deregulation of brain cell metabolism is commonly observed in low-grade brain cancers. Although the precise molecular mechanisms remain ill define, it is now clear that brain cancer cell often...