-
Resetting Microglia Activation in Offspring Exposed to Maternal High-Fat Diet
https://braincanada.ca/fr/subventions-financées/resetting-microglia-activation-in-offspring-exposed-to-maternal-high-fat-dietNutrition and diet are factors in life that contribute drastically to a person’s brain health, and overall quality of life, and high-fat diets can be considered a cause of many harmful physical and cognitive conditions. Project Overview Nutrition and diet are factors in life that contribute...
-
Reshaping Mitochondrial Efficiency and Integrity to Treat Parkinson’s Disease
https://braincanada.ca/fr/subventions-financées/reshaping-mitochondrial-efficiency-and-integrity-to-treat-parkinson-s-diseaseParkinson’s Disease (PD) is a debilitating neurodegenerative disease for which there is no cure. Project Overview Parkinson’s Disease (PD) is a debilitating neurodegenerative disease for which there is no cure. This movement disorder is thought to be due to the loss of a specific population of...
-
Restoration of mitochondrial function by activation of the NAD+/Sirtuin pathway to treat PD
https://braincanada.ca/fr/subventions-financées/restoration-of-mitochondrial-function-by-activation-of-the-nad-sirtuin-pathway-to-treat-pdParkinson’s Disease (PD) is a debilitating neurodegenerative disease for which there is no cure. Project Overview Parkinson’s Disease (PD) is a debilitating neurodegenerative disease for which there is no cure. The cardinal motor symptoms of PD are caused by the massive loss of neurons in a region...
-
Restoration of visual function: a cellular reprogramming and bioengineering approach
https://braincanada.ca/fr/subventions-financées/restoration-of-visual-function-a-cellular-reprogramming-and-bioengineering-approachThe retina is the part of the eye that is responsible for processing visual information. Project Overview The retina is the part of the eye that is responsible for processing visual information. Loss of neurons (nerve cells) in the central nervous system, which includes the brain and retina, is a...
-
RGNEF modulates protein misfolding in ALS
https://braincanada.ca/fr/subventions-financées/rgnef-modulates-protein-misfolding-in-alsDiscoveries made in Canada by the lab of Dr. Michael Strong over the past few years have implicated a protein called Rho guanidine nucleotide exchange factor (RGNEF) both pathologically and genetically in causing ALS. Project Overview Discoveries made in Canada by the lab of Dr. Michael Strong over...
-
Rising Star Award in Mental Health Research, in memory of Vivian Distler
https://braincanada.ca/fr/subventions-financées/rising-star-award-in-mental-health-research-in-memory-of-vivian-distlerPersonalized Modeling and Optimization of Transcranial Temporal Interference Stimulation in Major Depressive Disorder Project Overview Personalized Modeling and Optimization of Transcranial Temporal Interference Stimulation in Major Depressive Disorder Depression affects nearly 2 million...
-
Rising Star Award in Mental Health Research, in memory of Vivian Distler
https://braincanada.ca/fr/subventions-financées/rising-star-award-in-mental-health-research-in-memory-of-vivian-distler-1The Role of the Hypocretin-Dorsal Raphe Nucleus Circuit in Chronic Social Isolation and Acute Social Stress Project Overview The Role of the Hypocretin-Dorsal Raphe Nucleus Circuit in Chronic Social Isolation and Acute Social Stress Social behaviour is especially sensitive to stress, and isolation...
-
Road to Mental Readiness for Families and other Supportive Relationships
https://braincanada.ca/fr/subventions-financées/road-to-mental-readiness-for-families-and-other-supportive-relationshipsFirst responders, whose jobs commit them to persistent, repeated exposure to potentially triggering incidents, are at ongoing risk of developing mental health problems Project Overview First responders, whose jobs commit them to persistent, repeated exposure to potentially triggering incidents, are...
-
Role of ATF4 and P53 family transcription factors in the regulation of neuronal cell death
https://braincanada.ca/fr/subventions-financées/role-of-atf4-and-p53-family-transcription-factors-in-the-regulation-of-neuronal-cell-deathStroke is a leading cause of adult long term disability and the third leading cause of death in industrialized countries. Project Overview Stroke is a leading cause of adult long term disability and the third leading cause of death in industrialized countries. Brain cell death following stroke...
-
Role of microglia-derived factors in glial scar formation and axonal regeneration failure after spinal cord injury
https://braincanada.ca/fr/subventions-financées/role-of-microglia-derived-factors-in-glial-scar-formation-and-axonal-regeneration-failure-after-spinal-cord-injuryThe role of microglia in spinal cord injury (SCI) has remained obscure for decades. Project Overview The role of microglia in spinal cord injury (SCI) has remained obscure for decades. Microglia, the resident immune cells of the brain and spinal cord, were historically perceived as harmful to...