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Selective knockdown of misfolded SOD1 as a therapy for amyotrophic lateral sclerosis
https://braincanada.ca/fr/subventions-financées/selective-knockdown-of-misfolded-sod1-as-a-therapy-for-amyotrophic-lateral-sclerosisIn some cases of ALS, it is clear that specific inherited genetic changes (called mutations) can not only cause the disease, but can do so by creating a protein (the end product of genes that actually does a function in our cells) that has an abnormal, toxic function resulting in motor neuron...
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Selectively Targeting ERK Signaling to Treat Fragile X Syndrome and Autism
https://braincanada.ca/fr/subventions-financées/selectively-targeting-erk-signaling-to-treat-fragile-x-syndrome-and-autismAutism is one of the most prevalent neurodevelopmental disorders in Canada. It has a profound impact on the health, wellness and socioeconomic wellbeing of the patients and their families. Project Overview Autism is one of the most prevalent neurodevelopmental disorders in Canada. It has a profound...
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Self-disclosure about dementia on social media: evidence-informed guidance
https://braincanada.ca/fr/subventions-financées/self-disclosure-about-dementia-on-social-media-evidence-informed-guidanceIndividuals who engage on social media often disclose a personal dementia diagnosis or identify as a caregiver, yet little is known about the impact of that disclosure. Project Overview Individuals who engage on social media often disclose a personal dementia diagnosis or identify as a caregiver,...
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Semaine "Cerveau en tête
https://braincanada.ca/fr/à-propos-de/nouvelles-mises-à-jour/semaine-de-sensibilisation-au-cerveau-2026Brain Canada lance la Semaine Cerveau en tête 2026. Cette initiative mondiale réunit des organisations du monde entier pour sensibiliser le public et souligner l'importance cruciale de la santé du cerveau. En finançant des recherches révolutionnaires et en développant stratégiquement les talents de...
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Sensors for rapid detection of Alzheimer’s disease biomarker proteins
https://braincanada.ca/fr/subventions-financées/sensors-for-rapid-detection-of-alzheimer-s-disease-biomarker-proteinsBiomarkers are measurable indicators that help determine if a person may have, or be at risk of, developing a disease. Project Overview Biomarkers are measurable indicators that help determine if a person may have, or be at risk of, developing a disease. Changes in the brain can start more than a...
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Sensory development and integration in the common marmoset
https://braincanada.ca/fr/subventions-financées/sensory-development-and-integration-in-the-common-marmosetIn everyday life, we are solicited by numerous stimulations coming from different sensory modalities (e.g., visual, tactile, auditory…). Project Overview In everyday life, we are solicited by numerous stimulations coming from different sensory modalities (e.g., visual, tactile, auditory…). These...
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Serotonin circuit dysregulation in Alzheimer’s Disease
https://braincanada.ca/fr/subventions-financées/serotonin-circuit-dysregulation-in-alzheimer-s-diseaseThe early and severe loss of serotonin neurons along with the neuroprotective effects of SSRIs in Alzheimer’s Disease (AD) strongly implicates the serotonin system in disease pathology. Project Overview The early and severe loss of serotonin neurons along with the neuroprotective effects of SSRIs...
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Sex bias in autism spectrum disorders: Examining how sexual differentiation leads to divergent neurodevelopment and social behaviour
https://braincanada.ca/fr/subventions-financées/sex-bias-in-autism-spectrum-disorders-examining-how-sexual-differentiation-leads-to-divergent-neurodevelopment-and-social-behaviourMales are 4X more likely than females to develop Autism Spectrum Disorder (ASD), suggesting that the biology of sex development contributes to the risk of developing this neurodevelopmental condition. Project Overview Males are 4X more likely than females to develop Autism Spectrum Disorder (ASD),...
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Sex Differences in Association between hypertension and Cognitive Health: The Role of Small Vessel Disease
https://braincanada.ca/fr/subventions-financées/sex-differences-in-association-between-hypertension-and-cognitive-health-the-role-of-small-vessel-diseaseThe understanding of the factors responsible for the increased risk of cognitive problems in women remains limited. Project Overview The understanding of the factors responsible for the increased risk of cognitive problems in women remains limited. Determining the function of small vessel disease...
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Sex-Differences in Dopaminergic Regulation of Stroke Recovery in Rats
https://braincanada.ca/fr/subventions-financées/sex-differences-in-dopaminergic-regulation-of-stroke-recovery-in-ratsStrokes often cause brain damage that can severely affect motor function, particularly fine movements of the hands and digits. Project Overview Strokes often cause brain damage that can severely affect motor function, particularly fine movements of the hands and digits. The motor cortex is the main...