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14 results found

A Patient-Derived hiPSC Neuronal Platform for Drug Discovery in Parkinson’s Disease and Amyotrophic Lateral Sclerosis

Parkinson’s Disease (PD) and Amyotrophic Lateral Sclerosis (ALS) are two of the most common and devastating neurodegenerative diseases, affecting more than 2% of the population over the age of 65.

Project completed See Project & Researchers
Grant type
Platform grants
Area of Research
Neurodegeneration
Competition
CQDM - Brain Canada - Focus on Brain
Province
Québec
Start Date
2016

A national coordinating neuroinformatics framework for autism and related conditions

New approaches in neurodevelopmental research increasingly seek to integrate enormous amounts of data through sophisticated informatics so as to determine the relationship between genotype and phenotypes, both structural and functional, as they change over time during development.

Project completed See Project & Researchers
Grant type
Team grants
Area of Research
Neurodevlopment
Competition
Azrieli Neurodevelopment Research Program
Province
Québec
Start Date
2016

Douglas-Bell Canada Brain Bank, an essential platform for brain research in Canada

The Douglas-Bell Canada Brain Bank (DBCBB) houses and manages over 3,000 brains, as well as a large relational database containing demographic, clinical and developmental histories from the donors.

Project completed See Project & Researchers
Grant type
Platform grants
Area of Research
Mental Health
Competition
2014 Platform Grants
Province
Québec
Start Date
2015

Regulation of the stress granule proteome and transcriptome by TDP-43 in ALS: biomarkers and therapeutic targets

When cells are under stress, one of the reactions is to form tiny clumps called stress granules that protect important genetic information while protective mechanisms kick in.

Project completed See Project & Researchers
Grant type
Team grants
Area of Research
Neurodegeneration
Competition
ALS Arthur J. Hudson Translational Team Grant
Province
Québec
Start Date
2015