Funded Grants

Alzheimer’s disease (AD) is the most common cause of dementia, affecting memory, thinking, and daily functioning. AD is characterized by the buildup of two proteins, amyloid-β and tau. Specifically, tau protein is responsible for the loss of brain cells, leading to dementia. In addition to these two proteins, however, studies have also shown that inflammation plays an important role in how the disease develops and progresses.

Lu Wang, a Doctoral Student at McGill University, aims to compare the predictive accuracy of family history and polygenetic risk score for multiple sclerosis.

Impairments in social cognition (SC), such as difficulties in understanding emotions, social cues, and maintaining meaningful interactions, are key contributors to the loss of social inclusion and quality of life in individuals with neurodegenerative diseases (ND).

Investigating the role of EPG5 in Parkinson’s Disease pathogenesis

Jenna Hanrahan, a Doctoral Student at Memorial University of Newfoundland, aims to characterize the brain of a humanized mouse model of Huntington’s disease.

Amirhossein Jahani, a Postdoctoral Fellow at the University of Montreal, uses intracranial EEG to investigate how network interactions during the preictal phase (i.e., period preceding a seizure) may contribute to seizure initiation and propagation.

Amyotrophic Lateral Sclerosis (ALS) and frontotemporal dementia (FTD) are devastating diseases in which a protein called TDP-43 ends up in the wrong part of the cell, disrupting its normal role in managing RNA.

The Role of Brain Endocannabinoid Metabolism in Social Anxiety Disorder and Social Stress