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799 results found

Vascular innervation and blood-brain barrier dysfunction in Huntington’s disease using human iPSC-derived vascularized brain organoids.

“Vascular pathology, such as loss of neurovascular coupling and disruption of the blood-brain barrier (BBB), has been documented in Huntington’s disease (HD).


Area of Research
Neurodegeneration
Competition
Huntington Society of Canada - Brain Canada Undergraduate Student Fellowship
Province
Québec
Start Date
2025

Evaluating DLK activity in brain samples from Huntington’s disease patients

"Background:Within the realm of neurodegenerative diseases, there is still a lack of effective disease-modifying treatments. Huntington’s Disease (HD) is no less immune to this issue, with only symptomatic treatment options being available for patients."


Area of Research
Neurodegeneration
Competition
Huntington Society of Canada - Brain Canada Undergraduate Student Fellowship
Province
Ontario
Start Date
2025

Optimizing nanodiscs to improve antisense oligonucleotide delivery in the treatment of Huntington disease.

"Antisense oligonucleotides (ASOs) are synthetic single-stranded DNA/RNA that are useful in the targeting of mRNA sequences."


Area of Research
Other
Competition
Huntington Society of Canada - Brain Canada Undergraduate Student Fellowship
Province
Ontario
Start Date
2025

Investigating S-Nitrosylation of MCUB in Mitochondrial Calcium Dysregulation and Huntington’s Disease

"Huntington’s disease (HD) is an autosomal dominant neurodegenerative disorder characterized by progressive motor impairment and cognitive decline."


Area of Research
Neurodegeneration
Competition
Huntington Society of Canada - Brain Canada Undergraduate Student Fellowship
Province
Ontario
Start Date
2025

The Mesoscopic Integrated Neuroimaging Data (MIND) Platform

The MIND Platform is a groundbreaking initiative that will revolutionize brain research by allowing scientists to capture and analyze unprecedented detailed images of the brain at both large and small scales.


Grant type
Platform grants
Area of Research
Neurotechnology
Competition
2024 Platform Support Grants
Province
Ontario
Start Date
2025

Building Reproducible AI Frameworks for Brain Health with the Brain Health Data Challenge Platform

Neuroscience is on the brink of a digital revolution, where vast amounts of data from diverse individuals are supporting the creation of powerful predictive models of brain disorders.


Grant type
Platform grants
Area of Research
Mental Health
Competition
2024 Platform Support Grants
Province
Ontario
Start Date
2025

The Canadian Optogenetics and Vectorology Foundry

Optogenetics, defined as a technique where light-sensitive genes are introduced into brain cells to control their activity with light, allows researchers to precisely control nerve cell communication thereby, transforming brain research.


Grant type
Platform grants
Area of Research
Central Nervous System
Competition
2024 Platform Support Grants
Province
Québec
Start Date
2025

The University of British Columbia Genes, Cells and Circuits (UBC-GC2) platform for next-generation multiscale brain research

There is an urgent need for research that deepens our understanding of human brain function and uses this knowledge to accelerate therapeutic breakthroughs related to brain dysfunction.


Grant type
Platform grants
Area of Research
Multiple
Competition
2024 Platform Support Grants
Province
British Columbia
Start Date
2025

International Spinal Cord Injury Biobank (ISCIB): Promoting Global Spinal Cord Injury Research Through Human Biobanking

The International Spinal Cord Injury Biobank (ISCIB) is a multi-user biorepository with the mission of accelerating therapeutic development in traumatic spinal cord injury (SCI) through improved biological understanding of human injury, and the vision of serving as a global research resource where human SCI biospecimens are shared with researchers around the world.


Grant type
Platform grants
Area of Research
Injury
Competition
2024 Platform Support Grants
Province
British Columbia
Start Date
2025

Defining and targeting clonal hematopoiesis as a driver of glioblastoma growth

We discovered that approximately one fifth of people with the deadly brain tumour glioblastoma show age-related genetic changes in their blood cells called ‘clonal hematopoiesis’, or CHIP.


Grant type
Team grants
Area of Research
Cancer
Competition
2025 Translational Research Grants in Brain Cancer
Province
Ontario
Start Date
2025