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4 results found

Investigating mechanisms of altered lipid droplet dynamics in ALS

In Canada, the annual cost to care for individuals with neurodegenerative diseases is over $10.4 billion.

Project ongoing See Project & Researchers
Grant type
Team grants
Area of Research
Neurodegeneration
Competition
ALS Canada - Brain Canada Discovery Grants
Province
Québec
Start Date
2024

Investigating mechanisms that cause mitochondrial dysfunction and synaptic loss

Amyotrophic lateral sclerosis (ALS) is a fatal disease involving the gradual death of motor neurons. Motor neurons control the body’s movement.

Project ongoing See Project & Researchers
Grant type
Capacity building grants
Area of Research
Neurodegeneration
Competition
Future Leaders in Canadian Brain Research
Province
Québec
Start Date
2021

Enhancing the efficacy of heat shock protein inducers by cotreatment with a histone deacetylase inhibitor – A therapeutic strategy for ALS

In ALS and many other neurodegenerative diseases, one of the defining characteristics is that proteins can become misfolded and clump together, potentially damaging nerve cells.

Project ongoing See Project & Researchers
Grant type
Team grants
Area of Research
Neurodegeneration
Competition
ALS Arthur J. Hudson Translational Team Grant
Province
Québec
Start Date
2018

Mechanisms of Synaptic Dysfunction in Amyotrophic Lateral Sclerosis

This project will focus on unique roles of FUS (an ALS gene/protein) at the junction where neurons connect, called the synapse.

Project completed See Project & Researchers
Grant type
Capacity building grants
Area of Research
Neurodegeneration
Competition
ALS Canada - Brain Canada Career Transition Award
Province
Québec
Start Date
2016