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4 results found

Design and Development of Analogues of beta-Alanine as Therapeutics for AD

When brain cells are injured during Alzheimer’s disease, those cells may either die or become too electrically excitable.

Project ongoing See Project & Researchers
Area of Research
Neurodegeneration
Competition
Alzheimer Society Research Program (ASRP)
Province
Ontario
Start Date
2023

The Toronto Dementia Research Alliance (TDRA) Dementia Clinical Research Database: A Platform in Neurodegenerative Diseases

The Toronto Dementia Research Alliance will establish a clinical research platform that will provide a consistent and efficient approach to managing research and clinical care in patients with neurodegenerative conditions.

Project completed See Project & Researchers
Grant type
Platform grants
Area of Research
Neurodegeneration
Competition
2015 Platform Grants
Province
Ontario
Start Date
2015

Stimulating Endogenous Regeneration of Photoreceptors as a Potential Cure for Blindness

Sight is the most precious sense, and patients suffering vision loss endure a devastating experience. Blindness often results from the gradual death of photoreceptors, the retinal cells that perceive light.

Project completed See Project & Researchers
Grant type
Team grants
Area of Research
Central Nervous System
Competition
2014 MIRI Team Grants
Province
Ontario
Start Date
2015

Pharmacological Inhibition of TRPM2 in Neuroinflammation & Infection Models 

Alzheimer’s Disease (AD) is a neurodegenerative disorder that affects a growing population and poses a significant public health challenge. It is characterized by cognitive decline and memory loss, of which current therapies only manage symptoms or slow disease progression and does not treat the underlying disease progression.

Project ongoing See Project & Researchers
Grant type
Team grants
Area of Research
Neurodegeneration
Competition
Accelerator Grants: Neurodegeneration x Immunology
Province
Ontario