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Linking reduced cell-specific inhibition to abnormal brain activity in chronic stress

Depression is a leading cause of disability, with a large proportion of treatment-resistant patients. Recent studies have implicated reduced brain inhibition in human depression from a specific neuron type (SST), and new pharmacology boosting this reduced inhibition led to antidepressant and pro-cognitive effects in rodents.

Project ongoing See Project & Researchers
Grant type
Team grants
Area of Research
Mental Health
Competition
Brain Canada & Weizmann Institute o Science Team Grants
Province
Ontario
Start Date
2025