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Crosstalk between immune response and metabolic signaling: targeting leptin/AMPK axis to restore metabolic homeostasis in ALS

Increased metabolism (hypermetabolism) is a characteristic often associated with more aggressive, faster progressing cases of ALS.

Project ongoing See Project & Researchers
Grant type
Team grants
Area of Research
Neurodegeneration
Competition
ALS Canada - Brain Canada Discovery Grants
Province
Québec
Start Date
2021

Propagated protein misfolding of SOD1 in ALS: Exemplar for neurodegeneration

Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s disease, is a progressive fatal disease that affects the nerve cells responsible for muscle movement (motor neurons).

Project completed See Project & Researchers
Grant type
Team grants
Area of Research
Neurodegeneration
Competition
2012 MIRI Team Grants
Province
British Columbia
Start Date
2014