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3 results found

Harnessing mRNA translation to increase the neuroprotective potential of disease-associated microglia in neurodegenerative diseases

Microglia are the brain’s immune cells.

Project ongoing See Project & Researchers
Grant type
Team grants
Area of Research
Neurodegeneration
Competition
Brain Canada & Weizmann Institute o Science Team Grants
Province
Québec
Start Date
2024

Control of mRNA translation in Microglia response to Alzheimer’s disease pathology

Microglia are the brain’s immune cells, and their role is to protect the brain.

Project ongoing See Project & Researchers
Area of Research
Neurodegeneration
Competition
Alzheimer Society Research Program (ASRP)
Province
Québec
Start Date
2023

Treatment strategies for Autism Spectrum Disorders and Fragile-X Syndrome using mouse models, via translational control modulators

Aberrant control of protein synthesis (also termed translation) leads to pathological conditions like cancer, obesity, memory impairment and has been hypothesized to cause the development of Autism Spectrum Disorders (ASD) and Fragile-X syndrome (FXS).

Project completed See Project & Researchers
Grant type
Team grants
Area of Research
Neurodevlopment
Competition
Azrieli Neurodevelopment Research Program
Province
Québec
Start Date
2014