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3 results found

Spatial-temporal determinants of NMJs: from genes to function

Amyotrophic lateral sclerosis (ALS) is a disease where motor neurons, neurons that control the muscles to generate fundamental movements in our daily life, are gradually destroyed during the disease leading to paralysis and eventually death.


Grant type
Team grants
Area of Research
Neurodegeneration
Competition
ALS Canada - Brain Canada Discovery Grants
Province
Québec
Start Date
2024

Neuromuscular proteins as potential biomarkers in ALS

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by the loss of upper and lower motor neurons (MNs).


Grant type
Team grants
Competition
ALS Canada - Brain Canada Discovery Grants
Province
Québec
Start Date
2023

Enhancing the efficacy of heat shock protein inducers by cotreatment with a histone deacetylase inhibitor – A therapeutic strategy for ALS

In ALS and many other neurodegenerative diseases, one of the defining characteristics is that proteins can become misfolded and clump together, potentially damaging nerve cells.


Grant type
Team grants
Area of Research
Neurodegeneration
Competition
ALS Arthur J. Hudson Translational Team Grant
Province
Québec
Start Date
2018