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University of Alberta researchers have discovered a new method to identify the severity of Lou Gehrig’s disease in patients and track its progression. The U of A team, led by Sanjay Kalra, a professor in the Division of Neurology, has made progress toward an imaging biomarker for white-matter...

It’s a word that has a science-fiction sound to it, but, in fact, organoids are at the core of what scientist Jeff Wrana calls “revolutionizing biology.” Read the story here.

Vancouver, B.C. – November 24, 2005 – A team of researchers at the University of British Columbia has found a way to block the communication between brain cells that triggers drug cravings, a finding that could lead to new therapies to treat addiction and relapse as well as compulsive behaviours...

Tumors continuously change towards more aggressive and resistant forms. Project Overview Tumors continuously change towards more aggressive and resistant forms. Brain tumors illustrate the quandary of cancer evolution: despite standard-of-care treatment, the disease invariably progress and returns....

Even in the healthy brain, ageing is commonly associated with cognitive decline. Project Overview Even in the healthy brain, ageing is commonly associated with cognitive decline. The factors that could explain large inter-individual differences in the progression of the decline are still poorly...

The aims of the proposal were to examine the mechanism of how dopamine neurons degenerate in Parkinson (PD) animal models. Project Overview The aims of the proposal were to examine the mechanism of how dopamine neurons degenerate in Parkinson (PD) animal models. The work was centered on three...

The human brain is vulnerable to too much of mTOR signaling, An important neuronal pathway regulating neuronal development and activity. Project Overview The human brain is vulnerable to too much of mTOR signaling, An important neuronal pathway regulating neuronal development and activity. We study...

Addiction is a massive issue that spans generations and cultures. Project Overview Addiction is a massive issue that spans generations and cultures. Understanding and learning to help those suffering from addiction should continue to be a high- priority topic. Whether it’s looking to the past for...

We identified changes in the gene called IRF2BPL (Interferon Regulatory Factor 2 Binding Protein Like) as the cause of a severe brain disorder in children called NEDAMSS (Neurodevelopmental disorder with abnormal movements, loss of speech and seizures). Project Overview We identified changes in the...

Cannabis is one of the most commonly used recreational substances in Canada, yet its effects on brain blood flow remain poorly understood. Project Overview Cannabis is one of the most commonly used recreational substances in Canada, yet its effects on brain blood flow remain poorly understood....