Directory of funded grants

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774 results found

Development of a diagnostic amyloid-β seed amplification assay to discriminate between Alzheimer’s disease with and without cerebral amyloid angiopathy

  • Grant Type

    Capacity building grants

  • Area of research

    Neurodegeneration

  • Disease Area

    Alzheimer’s

  • Competition

    Alzheimer Society Research Program (ASRP)

  • Province

    Ontario

  • Start Date

    2025

  • Total Grant Amount

    $100,000

  • Health Canada Contribution

    $50,000

Project Overview

In Alzheimer’s disease (AD), the pathogenic amyloid-beta protein accumulates in the brain parenchyma and vessel walls. Deposition of amyloid-beta in the brain vasculature can lead to brain hemorrhages. Also, patients with abundant vascular amyloid-beta deposition are at increased risk of developing severe side effects upon treatment with the newly approved…

Project Ongoing

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Methylphenidate primed iTBS for apathy in neurocognitive disorders

  • Grant Type

    Capacity building grants

  • Area of research

    Neurodegeneration

  • Disease Area

    Alzheimer’s

  • Competition

    Alzheimer Society Research Program (ASRP)

  • Province

    Ontario

  • Start Date

    2025

  • Total Grant Amount

    $100,000

  • Health Canada Contribution

    $50,000

Project Overview

Apathy (reduced goal-directed behaviour) is common in persons with dementia and is associated with lower quality of life, increased dependence and faster decline. Two treatments were recently shown to be modestly effective: the first is an oral medication called methylphenidate; the second is brain stimulation. Looking at the way brain…

Project Ongoing

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Targeting Neuronal GFAP in Alzheimer’s Disease

  • Grant Type

    Capacity building grants

  • Area of research

    Neurodegeneration

  • Disease Area

    Alzheimer’s

  • Competition

    Alzheimer Society Research Program (ASRP)

  • Province

    Alberta

  • Start Date

    2025

  • Total Grant Amount

    $100,000

  • Health Canada Contribution

    $50,000

Project Overview

Alzheimer’s Disease (AD) affects many people and leads to memory loss and cognitive decline. It is linked to brain inflammation and changes in proteins like GFAP, which is usually found in support cells called astrocytes. Recent research has discovered that GFAP can also appear in neurons, potentially making these cells…

Project Ongoing

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In-Home Dementia-Centred DIY Adaptations and Innovations

  • Grant Type

    Capacity building grants

  • Area of research

    Neurodegeneration

  • Disease Area

    Alzheimer’s

  • Competition

    Alzheimer Society Research Program (ASRP)

  • Province

    Nova Scotia

  • Start Date

    2025

  • Total Grant Amount

    $100,000

  • Health Canada Contribution

    $50,000

Project Overview

This project explores how people living with dementia and their caregivers create clever do-it-yourself (DIY) solutions to make everyday tasks at home easier and safer. By collecting and analyzing these homegrown innovations, the project will then have these DIY innovators work with student and professional designers and engineers, who will…

Project Ongoing

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MitoDREADD-Gs: a new tool to identify the cell type-specific causal mechanisms in dementia

  • Grant Type

    Capacity building grants

  • Area of research

    Neurodegeneration

  • Disease Area

    Alzheimer’s

  • Competition

    Alzheimer Society Research Program (ASRP)

  • Province

    New Brunswick

  • Start Date

    2025

  • Total Grant Amount

    $100,000

  • Health Canada Contribution

    $50,000

Project Overview

Mitochondria are cellular components which provide the energy required by the brain. Any alteration of these small engines can lead to brain disorders, but their role in dementia remains poorly understood. We developed a tool named mitoDREADD-Gs. MitoDREADD-Gs is a transmembrane receptor which can be expressed in brain mitochondria of…

Project Ongoing

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