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676 results found

Dissecting the shared origins of schizophrenia and chronic cannabis use: A genomic investigation

  • Grant Type

    Capacity building grants

  • Area of research

    Mental Health

  • Disease Area

    Mental illness

  • Competition

    Rising Stars Trainee Awards

  • Province

    Ontario

  • Start Date

    2024

  • Total Grant Amount

    $10,000

  • Health Canada Contribution

    $5,000

Project Overview

Regular cannabis use is indisputably linked to schizophrenia. However, the causal nature and direction of this link is contentious and the biological mechanisms underpinning their relationship are poorly understood. Regular cannabis use is on the rise in Canada, so elucidating this relationship is timely and important. Genome-wide association studies (GWASs),…

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Characterization and modulation of the endocannabinoid system for treating Fragile X Syndrome

  • Grant Type

    Capacity building grants

  • Area of research

    Neurodevelopment

  • Disease Area

    Autism

  • Competition

    Rising Stars Trainee Awards

  • Province

    Québec

  • Start Date

    2024

  • Total Grant Amount

    $10,000

  • Health Canada Contribution

    $5,000

Project Overview

Fragile X syndrome (FXS) is the first inherited cause of intellectual disability and one of the most prevalent causes of autism spectrum disorders. Individuals with FXS do not produce a protein named FMRP. The absence of FMRP results in abnormal brain development and impaired synaptic transmission, which is the mechanism…

Project Ongoing

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2024 Dr. Hubert van Tol Travel Fellowship

  • Grant Type

    Capacity building grants

  • Area of research

    Injury

  • Disease Area

    Brain Injury

  • Competition

    Rising Stars Trainee Awards

  • Province

    Alberta

  • Start Date

    2024

  • Total Grant Amount

    $2,744

  • Health Canada Contribution

    $1,372

Project Overview

Alison Wilson, a Master's Student at the University of Calgary, aims to use magnetic resonance spectroscopy to investigate the pathophysiology of chronic post-traumatic headache. Alison used the Dr. Hubert van Tol Travel Fellowship to attend the EDITINGSCHOOL and Symposium for GABA and Advanced Magnetic Resonance Spectroscopy in Playa Del Carmen,…

Project Ongoing

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The Impact of Paediatric Brain Tumor Treatment on Structural and Functional Brain Connectivity

  • Grant Type

    Capacity building grants

  • Area of research

    Cancer

  • Disease Area

    Brain Cancer

  • Competition

    CRS Doctoral Research Awards

  • Province

    Ontario

  • Start Date

    2024

  • Total Grant Amount

    $70,000

  • Health Canada Contribution

    $35,000

Project Overview

Thanks to advances in cancer treatments, more than 80% of children treated for brain tumors now survive at least five years after their diagnosis. However, these treatments can often harm the brain, affecting both its structure and function. The brain's structure, particularly the white matter pathways that connect different regions,…

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Developing a “one-two punch” treatment paradigm for targeting glioblastoma

  • Grant Type

    Capacity building grants

  • Area of research

    Cancer

  • Disease Area

    Brain Cancer

  • Competition

    CRS Doctoral Research Awards

  • Province

    Ontario

  • Start Date

    2024

  • Total Grant Amount

    $70,000

  • Health Canada Contribution

    $35,000

Project Overview

By profiling the protein expression signatures of multiple patient-derived glioblastoma cell lines, we recently identified a major signalling pathway involved in glioblastoma cell migration. Excitingly, we showed that chemical inhibition of a key protein involved in regulating this pathway significantly reduced the infiltration of three glioblastoma cell lines. While inhibiting…

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