770 results found
PET imaging of Alzheimer’s-induced inflammation to monitor progression and therapy response using a novel fructose-based radiotracer
Project Overview
One of the key processes driving Alzheimer’s Disease is inflammation in the brain, the severity of which may predict the severity of disease. Currently, doctors use special brain scans to look for signs of Alzheimer’s Disease, but these scans can’t tell if inflammation is present. This project aims to develop…
Project Ongoing
See the project and researchersSignatures of early life stress as a risk factor for Alzheimer’s disease
Project Overview
Our project investigates how childhood stress may increase the risk of developing Alzheimer’s Disease (AD) later in life. We know that stress during early development can affect a brain chemical called serotonin, which plays a key role in memory and mood - two areas that are also affected in AD.…
Project Ongoing
See the project and researchersEnsuring equitable access to inpatient rehabilitation for people living with dementia: An effectiveness-implementation randomized trial
Project Overview
One in five older adults with dementia is hospitalized each year. One in three hospitalized older adults will lose independence in transferring, eating, ambulating, dressing, or bathing, which increases nursing home admission risk; this risk is 36% greater in people living with dementia (PLWD). Rehabilitation could decrease this risk, but…
Project Ongoing
See the project and researchersA Pilot Randomized Trial of a Digital App, WhatMatters to enable Person-Centred Care
Project Overview
Person-centred care is vital for dementia patients in hospitals to prevent stress-induced behaviors. My team has developed WhatMatters, an app that allows family members to remotely share reassuring videos, familiar photos and music to comfort patients in hospital. This study assesses the effectiveness of the mobile app, WhatMatters, in improving…
Project Ongoing
See the project and researchersNeighbourhood Wellbeing and Dementia
Project Overview
Most people living with dementia (PLWD) live in community supported by informal care partners. Continued access to community is a human right, and linked to better physical, mental, and social health. We aim to improve neighbourhoods for PLWD and care partners from a planning perspective, examining wayfinding, infrastructure availability and…