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Sex differences in exercise efficacy: Possible role of BDNF and stress axis
https://braincanada.ca/fr/subventions-financées/sex-differences-in-exercise-efficacy-possible-role-of-bdnf-and-stress-axisResearch suggests that exercise can help improve brain health and decrease the risk of dementia, but there is variation in the benefit of different exercise interventions. Project Overview Research suggests that exercise can help improve brain health and decrease the risk of dementia, but there is...
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Sex differences in modulation of serotonergic circuits by the neuropeptide corticotropin releasing factor
https://braincanada.ca/fr/subventions-financées/sex-differences-in-modulation-of-serotonergic-circuits-by-the-neuropeptide-corticotropin-releasing-factorAnxiety disorders disproportionately affect women: their chances of developing an anxiety disorder are twice as high than for men. Project Overview Anxiety disorders disproportionately affect women: their chances of developing an anxiety disorder are twice as high than for men. Fundamental research...
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Sex differences in the innate immune response associated with Parkinson’s Disease
https://braincanada.ca/fr/subventions-financées/sex-differences-in-the-innate-immune-response-associated-with-parkinson-s-diseaseAge is the most important risk factor for Parkinson’s Disease (PD), followed by sex, with a higher risk in males. Project Overview Age is the most important risk factor for Parkinson’s Disease (PD), followed by sex, with a higher risk in males. Studies show that brain inflammation occurs early in...
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Sex-related differences in visuomotor skills, cognition, and emotionality following concussive injury
https://braincanada.ca/fr/subventions-financées/sex-related-differences-in-visuomotor-skills-cognition-and-emotionality-following-concussive-injuryThe proposed research project aims to study the differences in brain function behaviour between male and female university athletes who have experienced a concussion. Project Overview The proposed research project aims to study the differences in brain function behaviour between male and female...
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Sexual Development and Inflammatory Bowel Disease: The Microbiome- Hormone-Brain Axis
https://braincanada.ca/fr/subventions-financées/sexual-development-and-inflammatory-bowel-disease-the-microbiome-hormone-brain-axisThe microbes living in our gut have recently been found to affect important developmental processes such as brain development and hormonal regulation during puberty. Project Overview The microbes living in our gut have recently been found to affect important developmental processes such as brain...
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ShARP: Screenable assays for RNA-binding proteins involved in brain disorders and diseases
https://braincanada.ca/fr/subventions-financées/sharp-screenable-assays-for-rna-binding-proteins-involved-in-brain-disorders-and-diseasesBrain disorders such as autism, major depressive disorder and Alzheimer’s disease are among the greatest medical challenges of our era. Project Overview Brain disorders such as autism, major depressive disorder and Alzheimer’s disease are among the greatest medical challenges of our era. Many drugs...
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Signatures of early life stress as a risk factor for Alzheimer’s disease
https://braincanada.ca/fr/subventions-financées/signatures-of-early-life-stress-as-a-risk-factor-for-alzheimer-s-diseaseOur project investigates how childhood stress may increase the risk of developing Alzheimer’s Disease (AD) later in life. Project Overview Our project investigates how childhood stress may increase the risk of developing Alzheimer’s Disease (AD) later in life. We know that stress during early...
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Single-cell multi-omics to uncover mechanisms of patient glioblastoma heterogeneity and recurrence
https://braincanada.ca/fr/subventions-financées/single-cell-multi-omics-to-uncover-mechanisms-of-patient-glioblastoma-heterogeneity-and-recurrenceBrain cancer is rarely curative and urgently needs novel transformative treatments. Project Overview Brain cancer is rarely curative and urgently needs novel transformative treatments. Glioblastoma (GBM) is the most common primary malignant brain tumor in adults. It is also among the most...
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SLAP-CAN In vivo Imaging Facility
https://braincanada.ca/fr/subventions-financées/slap-can-in-vivo-imaging-facilityThe central nervous system (CNS, the brain and spinal cord together) is perhaps the most complex biological entity in the world. Project Overview The central nervous system (CNS, the brain and spinal cord together) is perhaps the most complex biological entity in the world. The CNS allows us to...
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Sleep, cognition, and inflammation following natural or surgical menopause
https://braincanada.ca/fr/subventions-financées/sleep-cognition-and-inflammation-following-natural-or-surgical-menopauseAlzheimer’s disease disproportionately affects women and emerging evidence suggests there may be unique biological and lifestyle factors that underlie these differences. Project Overview Alzheimer’s disease disproportionately affects women and emerging evidence suggests there may be unique...