Funded Grants

Addiction is a massive issue that spans generations and cultures.

To obtain a more inclusive understanding of vascular contributions to cognitive impairment and dementia (VCID) in women, we will investigate the relationship between vascular health and cognition in women belonging to Canada’s three largest ethnic groups (South Asian, Chinese, and White).

In the era of climate change-related disasters and a globally disruptive pandemic, people worldwide are grappling with the question of how to foster resilience.

Major depression is common, highly prevalent, potentially lethal, affecting 10% of individuals with significant increase between 2015-2020, and 2-3-fold higher incidence in women compared to men.

The understanding of the factors responsible for the increased risk of cognitive problems in women remains limited.

Pregnancy and the postpartum period are high risk for depression onset and other psychiatric disorders in the birthing parent.

Endogenous retrovirus-K (ERVK) is a genomic viral symbiont that contributes towards ALS neuropathology.

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder with no known cure, leading to progressive loss of motor function and ultimately the death of the patient.

Rationale: Cortical hyperexcitability has been identified to be a potential driver of ALS pathology leading to excitotoxicity and degeneration of upper motor neurons (UMNs)in the primary motor cortex (M1) and the subsequent degeneration of lower motor neurons (LMNs) in the spinal cord.

Almost all amyotrophic lateral sclerosis (ALS) is accompanied by neuronal cytoplasmic aggregates of TAR DNA-binding protein-43 (TDP-43).