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889 results found

Health system implications of novel therapeutics for Alzheimer’s Disease: Supporting capacity planning with real-world evidence

Close to 600,000 Canadians currently live with Alzheimer’s disease and related dementias, but effective therapies are limited and focus on symptom management rather than a cure.


Grant type
Capacity building grants
Area of Research
Neurodegeneration
Competition
Alzheimer Society Research Program (ASRP)
Province
Ontario
Start Date
2024

Targeting the USP19 deubiquitinating enzyme for the treatment of Alzheimer’s disease

Alzheimer’s disease progresses over time due to the spreading of aggregates of tau protein and amyloid protein from unaffected to affected regions of the brain.


Grant type
Capacity building grants
Area of Research
Neurodegeneration
Competition
Alzheimer Society Research Program (ASRP)
Province
Québec
Start Date
2024

Does psilocybin increase synaptic density in the brain in patients with mild cognitive impairment?

Amnestic mild cognitive impairment (aMCI) is viewed as a precursor to Alzheimer’s Disease (AD) for which there are no effective treatments.


Grant type
Capacity building grants
Area of Research
Neurodegeneration
Competition
Alzheimer Society Research Program (ASRP)
Province
Ontario
Start Date
2024

Genes involved in APP-mediated GLUT1 regulation

Alzheimer’s disease is the most common form of dementia.


Grant type
Capacity building grants
Area of Research
Neurodegeneration
Competition
Alzheimer Society Research Program (ASRP)
Province
Québec
Start Date
2024

Targeting the microbiota-gut-brain axis with diet and exercise interventions in individuals with subjective cognitivedecline

Individuals with or at increased risk of Alzheimer’s disease (AD) have an altered community of microbes(microbiome) within the intestinal tract.


Grant type
Capacity building grants
Area of Research
Neurodegeneration
Competition
Alzheimer Society Research Program (ASRP)
Start Date
2024

Brain Health Resources and Integrated Diversity (BRAID) Hub

The BRAID Hub (Brain health Resources And Integrated Diversity Hub) addresses critical gaps in Canada’s dementia care system.


Area of Research
Neurodegeneration
Competition
Canadian Brain Health and Cognitive Impairment in Aging Research Knowledge Mobilization (KM) Hub
Province
Ontario
Start Date
2024

MicroRNA biomarkers: Using Tears to Assess Alzheimer’s Disease

Alzheimer’s disease (AD) is the most common form of dementia and 7th leading cause of death in North-America.


Grant type
Capacity building grants
Area of Research
Neurodegeneration
Competition
Alzheimer Society Research Program (ASRP)
Province
British Columbia
Start Date
2024

Evaluating the histone variant macroH2A1.1 as a master regulator of PARP1-Sirt1 balance in Alzheimer’s disease

Alzheimer’s Disease (AD) is characterized by memory decline and neuronal pathology, including amyloid β (Aβ)plaques and oxidative stress.


Grant type
Capacity building grants
Area of Research
Neurodegeneration
Competition
Alzheimer Society Research Program (ASRP)
Province
Ontario
Start Date
2024

Assessing the Efficacy of a Hypomethylating Agent to Decrease Post-Pneumonia Cognitive Impairments

Infections like pneumonia can speed up dementia. Vaccinations can prevent infections but don’t always work in older adults.


Grant type
Capacity building grants
Area of Research
Neurodegeneration
Competition
Alzheimer Society Research Program (ASRP)
Province
Ontario
Start Date
2024

Boosting self-cueing to maintain independence in dementia

Everyday activities such as cooking often become difficult for people living with dementia.


Grant type
Capacity building grants
Area of Research
Neurodegeneration
Competition
Alzheimer Society Research Program (ASRP)
Province
Ontario
Start Date
2024