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860 results found

Understand mTOR hyperactivation during cellular interactions using a single-cell approach

The human brain is vulnerable to too much of mTOR signaling, An important neuronal pathway regulating neuronal development and activity.


Grant type
Capacity building grants
Area of Research
Neurodevelopment
Competition
Future Leaders in Canadian Brain Research
Province
Québec
Start Date
2023

Decoding the Spatial Architecture of Newborn Brain Injury

Infants born early (preterm) are at risk for brain injury and long term neurodevelopmental challenges, including delays in walking, language development, and school-aged cognitive performance.


Grant type
Capacity building grants
Area of Research
Neurodevelopment
Competition
Future Leaders in Canadian Brain Research
Province
Ontario
Start Date
2023

From Substitution to Participation: Recognizing Persons with Dementia as Social Citizens

The Canadian Charter of Rights for People with Dementia states that persons with dementia must receive the support needed to participate as fully as possible in decisions that affect them.


Area of Research
Neurodegeneration
Competition
Alzheimer Society Research Program (ASRP)
Province
Québec
Start Date
2023

Disrupting VCP/p97-GluA1 as a novel therapeutic intervention to restore synaptic plasticity in Alzheimer’s disease: A cryo-electron microscopy (cryo-EM) based approach

Many proteins in our brain are responsible for memory and learning.


Area of Research
Neurodegeneration
Competition
Alzheimer Society Research Program (ASRP)
Province
British Columbia
Start Date
2023

Amyloid deposition and the glymphatic system assessed simultaneously in Alzheimer’s disease using PET/MRI

Poor sleep is a known risk factor for Alzheimer’s disease.


Area of Research
Neurodegeneration
Competition
Alzheimer Society Research Program (ASRP)
Province
Ontario
Start Date
2023

Quantitative fluorescence spectroscopy of the central nervous system amylome

It is generally acknowledged that accumulation of misfolded proteins (amyloid) in brains of Alzheimer’s disease patients is a key disease phenomenon.


Area of Research
Neurodegeneration
Competition
Alzheimer Society Research Program (ASRP)
Province
Alberta
Start Date
2023

Control of mRNA translation in Microglia response to Alzheimer’s disease pathology

Microglia are the brain’s immune cells, and their role is to protect the brain.


Area of Research
Neurodegeneration
Competition
Alzheimer Society Research Program (ASRP)
Province
Québec
Start Date
2023

Alternative Strategies to Prevent Oral Pathogens Infection and Battle Alzheimer’s Disease


Area of Research
Neurodegeneration
Competition
Alzheimer Society Research Program (ASRP)
Province
Québec
Start Date
2023

Sensors for rapid detection of Alzheimer’s disease biomarker proteins

Biomarkers are measurable indicators that help determine if a person may have, or be at risk of, developing a disease.


Area of Research
Neurodegeneration
Competition
Alzheimer Society Research Program (ASRP)
Province
British Columbia
Start Date
2023

An intergenerational behavioural intervention to enhance physical activity in older adults at risk for Alzheimer’s disease

Physical activity is one of the most important means of reducing risk of dementia.


Area of Research
Neurodegeneration
Competition
Alzheimer Society Research Program (ASRP)
Province
Québec
Start Date
2023