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839 results found

Neuromuscular proteins as potential biomarkers in ALS

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by the loss of upper and lower motor neurons (MNs).


Grant type
Team grants
Competition
ALS Canada - Brain Canada Discovery Grants
Province
Québec
Start Date
2023

blooD prEssure management in sTroke following EndovasCular Treatment (DETECT)

Most strokes occur from clots blocking vessels that supply blood flow to the brain.


Grant type
Team grants
Area of Research
Injury
Competition
Canadian Stroke Consortium-Brain Canada-Heart and Stroke Foundation of Canada 2022 Stroke Clinical Research Catalyst Grants
Province
Ontario
Start Date
2023

Deepening our understanding of G3BP1 and its paralog G3BP2 to facilitate accurate therapeutic development for ALS/FTD

While significant efforts have been made worldwide, the development of an effective therapy to significantly slow or halt ALS disease progression has remained elusive.


Grant type
Team grants
Competition
ALS Canada - Brain Canada Discovery Grants
Province
Québec
Start Date
2023

Modeling ALS progression by applying neuroinformatics to a novel in vitro human 3D tri-culture model of the disease

Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disease in which the motor neurons degenerate, leading to symptoms of muscle weakness and progressive paralysis, resulting in the death of patients from respiratory failure.


Grant type
Team grants
Competition
ALS Canada - Brain Canada Discovery Grants
Province
Québec
Start Date
2023

Mechanisms of focused ultRasound mEdiated BrAin cLeAniNg Coupled with enhanced mEchanosensation (REBALANCE)

Focused ultrasound (FUS) is a non-invasive, ground-breaking technique suggested for the treatment of Alzheimer’s disease (AD).


Grant type
Team grants
Competition
EU Joint Programme – Neurodegenerative Disease Research (JPND)
Province
Ontario
Start Date
2023

The impact of ALS disease variants on regulation of heat shock protein life cycles – Implications for neuronal proteostasis

The abnormal accumulation of misfolded proteins and aggregates is the hallmark of multiple forms of ALS and other neurodegenerative diseases.


Grant type
Team grants
Competition
ALS Canada - Brain Canada Discovery Grants
Province
Québec
Start Date
2023

The TeleTaCAS Randomized Controlled Feasibility Trial

Stroke happens to 62,000 people each year in Canada.


Grant type
Team grants
Area of Research
Injury
Competition
Canadian Stroke Consortium-Brain Canada-Heart and Stroke Foundation of Canada 2022 Stroke Clinical Research Catalyst Grants
Province
Alberta
Start Date
2023

Supine cycling with lower body negative pressure: a novel treatment for concussion

The main aim of this project is to examine the efficacy of the non-pharmacological intervention of lower body negative pressure (LBNP) with head up tilt on cerebral blood flow and concussion symptoms during exercise in individuals with persisting symptoms.


Grant type
Capacity building grants
Competition
2022 brain Changes Initiative Award for Traumatic Brain Injury - Special Purpose Grants
Start Date
2023

A Drug Screening Assay to Reduce LINGO-1 Amounts in Neurons

The LINGO-1 protein is strongly associated with Alzheimer’s disease and is a novel drug target.


Grant type
Capacity building grants
Area of Research
Neurodegeneration
Competition
Alzheimer's Association International Grant Program
Province
Québec
Start Date
2022

Mind Over Matter Magazine (Volume 14)


Grant type
Knowledge translation grants
Area of Research
Knowledge Translation
Competition
Other
Province
Ontario
Start Date
2022