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858 results found

Accelerating the Reach of the Driving and Dementia Roadmap

This project focuses on accelerating awareness about the importance of the issue of driving cessation by promoting the uptake of the Driving and Dementia Roadmap (DDR).


Grant type
Knowledge translation grants
Area of Research
Neurodegeneration
Competition
Alzheimer's Society of Canada - Brain Canada Foundation Knowledge Translation and Exchange Accelerator Grants
Province
Ontario
Start Date
2023

Rational targeting of FUS and TDP-43 protein assemblies for diagnostics and treatment of ALS

The project addresses a grand challenge in ALS, the integration of a multi-targeted and personalized approach to patients with a rational strategy focusing on a unifying pivotal mechanism of the disease.


Grant type
Team grants
Competition
ALS Canada - Brain Canada Discovery Grants
Province
Alberta
Start Date
2023

Elucidating the basis for ubiquitination of misfolded ALS proteins by E3 ligase Enzymes

A pathologic feature in both sporadic and familial ALS patients is the presence of large neuronal inclusions enriched with misfolded proteins, including SOD1, TDP43 and FUS that are frequently modified with the small protein ubiquitin (Ub)


Grant type
Team grants
Competition
ALS Canada - Brain Canada Discovery Grants
Province
Ontario
Start Date
2023

Accelerating the Integration of Be EPIC-VR in Dementia Care

Personal support workers provide the most formal care to people living with dementia.


Grant type
Knowledge translation grants
Area of Research
Neurodegeneration
Competition
Alzheimer's Society of Canada - Brain Canada Foundation Knowledge Translation and Exchange Accelerator Grants
Province
Ontario
Start Date
2023

Neuromuscular proteins as potential biomarkers in ALS

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by the loss of upper and lower motor neurons (MNs).


Grant type
Team grants
Competition
ALS Canada - Brain Canada Discovery Grants
Province
Québec
Start Date
2023

Axonal degeneration as a therapeutic target for ALS

One of the neuron’s most impressive morphological features is their long axonal projections, which are the basis of the complex, precise, and fast-firing neuronal network.


Grant type
Team grants
Competition
ALS Canada - Brain Canada Discovery Grants
Province
Québec
Start Date
2023

Spreading the Impact of the Dementia Resources for Eating, Activity and Meaningful inclusion (DREAM) Toolkit

This grant builds on two related projects: the Dementia-Inclusive Choices for Exercise (DICE) project (funded by the Alzheimer Society Research Program); and the Dementia Resources for Eating, Activity, and Meaningful inclusion (DREAM) project.


Grant type
Knowledge translation grants
Area of Research
Neurodegeneration
Competition
Alzheimer's Society of Canada - Brain Canada Foundation Knowledge Translation and Exchange Accelerator Grants
Province
Ontario
Start Date
2023

Modeling ALS progression by applying neuroinformatics to a novel in vitro human 3D tri-culture model of the disease

Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disease in which the motor neurons degenerate, leading to symptoms of muscle weakness and progressive paralysis, resulting in the death of patients from respiratory failure.


Grant type
Team grants
Competition
ALS Canada - Brain Canada Discovery Grants
Province
Québec
Start Date
2023

Improving function and quality of life: rehabilitation for long-term care residents with moderate to severe dementia

Develop and disseminate a training program for rehabilitation providers working with long-term care residents with dementia.


Grant type
Knowledge translation grants
Area of Research
Neurodegeneration
Competition
Alzheimer's Society of Canada - Brain Canada Foundation Knowledge Translation and Exchange Accelerator Grants
Province
Nova Scotia
Start Date
2023

Remote ischemic preconditioning treatment in amyotrophic lateral sclerosis

RATIONALE: There are no effective disease modifying therapies for amyotrophic lateral sclerosis (ALS).


Grant type
Team grants
Competition
ALS Canada - Brain Canada Discovery Grants
Province
Alberta
Start Date
2023