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Mind Over Matter Magazine (Volume 15)
https://braincanada.ca/funded-grants/mind-over-matter-magazine-volume-15Partners and Donors Women's Brain Health Initiative
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Mind Over Matter Magazine (Volume 16)
https://braincanada.ca/funded-grants/mind-over-matter-magazine-volume-16Partners and Donors Women's Brain Health Initiative
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Mind Over Matter Magazine (Volume 17)
https://braincanada.ca/funded-grants/mind-over-matter-magazine-volume-17Partners and Donors Women's Brain Health Initiative
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Mind Over Matter Magazine (Volume 9)
https://braincanada.ca/funded-grants/mind-over-matter-magazine-volume-9Partners and Donors Women's Brain Health Initiative
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Misfolded SOD1 in ALS pathogenesis
https://braincanada.ca/funded-grants/misfolded-sod1-in-als-pathogenesisThe first genetic cause of ALS to be discovered (in 1993) encoded a mutation in protein called superoxide dismutase 1 (SOD1). Project Overview The first genetic cause of ALS to be discovered (in 1993) encoded a mutation in protein called superoxide dismutase 1 (SOD1). Decades later, it is largely...
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Mitochondrial calcium uptake and targeted therapeutics
https://braincanada.ca/funded-grants/mitochondrial-calcium-uptake-and-targeted-therapeuticsStroke is the sudden death of brain cells caused by insufficient blood supply to the brain. Parts of the brain that enable us to walk and talk are often damaged most by a stroke. Project Overview Stroke is the sudden death of brain cells caused by insufficient blood supply to the brain. Parts of...
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Mitochondrial dysfunction and neuronal demise: Insights provided by Parkinson’s disease genes
https://braincanada.ca/funded-grants/mitochondrial-dysfunction-and-neuronal-demise-insights-provided-by-parkinson-s-disease-genesConverging research efforts have recently identified five genes that are associated with familial Parkinson’s Disease (PD), a condition associated with severe motor dysfunction and loss of dopamine-producing cells in the brain. Project Overview Converging research efforts have recently identified...
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Mitochondrial dysfunction and vulnerability to oxidative stress in induced dopaminergic neurons derived from idiopathic Parkinson’s disease patients
https://braincanada.ca/funded-grants/mitochondrial-dysfunction-and-vulnerability-to-oxidative-stress-in-induced-dopaminergic-neurons-derived-from-idiopathic-parkinson-s-disease-patientsParkinson’s Disease (PD) is an age-associated movement disorders, mainly caused by the death of dopamine cells in the brain. Project Overview Parkinson’s Disease (PD) is an age-associated movement disorders, mainly caused by the death of dopamine cells in the brain. Over 90% of PD cases are...
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MitoDREADD-Gs: a new tool to identify the cell type-specific causal mechanisms in dementia
https://braincanada.ca/funded-grants/mitodreadd-gs-a-new-tool-to-identify-the-cell-type-specific-causal-mechanisms-in-dementiaMitochondria are cellular components which provide the energy required by the brain. Any alteration of these small engines can lead to brain disorders, but their role in dementia remains poorly understood. Project Overview Mitochondria are cellular components which provide the energy required by...
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Modeling ALS progression by applying neuroinformatics to a novel in vitro human 3D tri-culture model of the disease
https://braincanada.ca/funded-grants/modeling-als-progression-by-applying-neuroinformatics-to-a-novel-in-vitro-human-3d-tri-culture-model-of-the-diseaseAmyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disease in which the motor neurons degenerate, leading to symptoms of muscle weakness and progressive paralysis, resulting in the death of patients from respiratory failure. Project Overview Amyotrophic Lateral Sclerosis (ALS) is a...