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Mouse brain imaging for neurodevelopmental disorders
https://braincanada.ca/funded-grants/mouse-brain-imaging-for-neurodevelopmental-disordersThe project provides state of the art mouse brain imaging to researchers in Canada working on models of neurodevelopmental disorders. Project Overview The project provides state of the art mouse brain imaging to researchers in Canada working on models of neurodevelopmental disorders. The use of...
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MouseTRAP: The Mouse Translational Research Accelerator Platform
https://braincanada.ca/funded-grants/mousetrap-the-mouse-translational-research-accelerator-platformNeurodegenerative conditions such as Alzheimer’s and Parkinson’s disease profoundly affect aspects of cognition including memory Project Overview Neurodegenerative conditions such as Alzheimer’s and Parkinson’s disease profoundly affect aspects of cognition including memory, attention, decision...
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Movement Into a Mission
https://braincanada.ca/about/news-updates/movement-into-a-missionOn Sunday, October 26th, Riverdale Farm in Toronto came alive with laughter, energy, and purpose as dozens gathered for the first-ever Functional Phil Community Walk. At the heart of this fundraiser was Philippe Marsan, better known to his clients and community as Functional Phil. On Sunday,...
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Moving discoveries from the lab towards real-world applications
https://braincanada.ca/about/news-updates/moving-discoveries-from-the-lab-towards-real-world-applicationsMRI technician prepares a participant for an MRI scan. Canada has world-class neuroscience talent, leading to high-impact discovery research in brain science. However, turning leading science into the products that will affect the course of a patient’s health requires, in part, the existence of...
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MRI Biomarkers of Cerebral Degeneration in ALS and their Pathological Validation
https://braincanada.ca/funded-grants/mri-biomarkers-of-cerebral-degeneration-in-als-and-their-pathological-validationA biological marker, or “biomarker” for short, is a measurable indicator associated with a disease state that helps determine risk, severity and response to therapy. Project Overview A biological marker, or “biomarker” for short, is a measurable indicator associated with a disease state that helps...
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Multi-modal neuroimaging biomarkers of Parkinson’s disease progression
https://braincanada.ca/funded-grants/multi-modal-neuroimaging-biomarkers-of-parkinson-s-disease-progressionParkinson’s disease (PD) is one of the most common neurodegenerative disorders in the world. Project Overview Parkinson’s disease (PD) is one of the most common neurodegenerative disorders in the world. PD can manifest and develop in a variety of ways for different patients, and it is currently not...
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Multi-scale analyses of brain connectivity and dynamics in autism spectrum conditions
https://braincanada.ca/funded-grants/multi-scale-analyses-of-brain-connectivity-and-dynamics-in-autism-spectrum-conditionsAutism spectrum disorder (ASD) affects approximately 1 in 70 children and is associated to a considerable burden for affected individuals, their families, and health care at large. Project Overview Autism spectrum disorder (ASD) affects approximately 1 in 70 children and is associated to a...
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Muscle-targeted therapy for ALS
https://braincanada.ca/funded-grants/muscle-targeted-therapy-for-alsIn ALS, the disease is characterized by degeneration of motor neurons and an inability of the brain to signal the muscles to move, resulting in paralysis. Project Overview In ALS, the disease is characterized by degeneration of motor neurons and an inability of the brain to signal the muscles to...
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Music-Based Interventions to Engage Memory in Individuals Living with Dementia
https://braincanada.ca/funded-grants/music-based-interventions-to-engage-memory-in-individuals-living-with-dementiaEven though memory loss is one of the most debilitating features of dementia, several studies has revealed the ability of music to trigger the recall of old memories is relatively preserved in people living with dementia. Yet, we don’t exactly what feature of music activates memories. This goal of...
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Mutations in the gene encoding the molecular chaperones DnaJC7 in amyotrophic lateral sclerosis
https://braincanada.ca/funded-grants/mutations-in-the-gene-encoding-the-molecular-chaperones-dnajc7-in-amyotrophic-lateral-sclerosisIn 2019, a team of scientists led by co-recipient Dr. Sali Farhan discovered a new genetic cause of ALS called DNAJC7. Project Overview In 2019, a team of scientists led by co-recipient Dr. Sali Farhan discovered a new genetic cause of ALS called DNAJC7. Subsequent work revealed that mutations in...