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Molecular and behavioural assessment of a potential fetal Cannabis spectrum disorder in the rat
https://braincanada.ca/funded-grants/molecular-and-behavioural-assessment-of-a-potential-fetal-cannabis-spectrum-disorder-in-the-ratCanada recently became the first G7 nation to legalize Cannabis for medicinal and recreational use. Project Overview Canada recently became the first G7 nation to legalize Cannabis for medicinal and recreational use. There is a recent and growing false belief that Cannabis can reduce nausea during...
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Molecular characterization of transcriptional repressor capicua in GBM
https://braincanada.ca/funded-grants/molecular-characterization-of-transcriptional-repressor-capicua-in-gbmMalignant gliomas, including oligodendrogliomas (OD) and glioblastomas (GBM), are currently incurable brain tumours with few effective treatment options. Project Overview Malignant gliomas, including oligodendrogliomas (OD) and glioblastomas (GBM), are currently incurable brain tumours with few...
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Molecular heterogeneity drives the clinical behaviour of childhood medulloblastoma
https://braincanada.ca/funded-grants/molecular-heterogeneity-drives-the-clinical-behaviour-of-childhood-medulloblastomaBrain cancer is the most common type of solid cancer in children in Canada, and medulloblastoma is the most common malignant brain cancer of childhood. Project Overview Brain cancer is the most common type of solid cancer in children in Canada, and medulloblastoma is the most common malignant brain...
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Molecular origins of childhood brain cancer
https://braincanada.ca/funded-grants/molecular-origins-of-childhood-brain-cancerPediatric high-grade gliomas are incurable brain cancers. Project Overview Pediatric high-grade gliomas are incurable brain cancers. Sequencing the tumor specimens has shown that most cases do not have obvious mutations that are known to cause cancer. It is therefore not known what causes, or...
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Molecular processes underlying neuromuscular junction denervation in humans with ALS
https://braincanada.ca/funded-grants/molecular-processes-underlying-neuromuscular-junction-denervation-in-humans-with-alsAmyotrophic lateral sclerosis (ALS) is marked by dysfunction and degeneration of neuromuscular junctions (NMJ). Project Overview Amyotrophic lateral sclerosis (ALS) is marked by dysfunction and degeneration of neuromuscular junctions (NMJ). This can be one of the earliest pathological processes...
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Molecular regulators of extracellular matrix remodeling during Amyotrophic Lateral Sclerosis
https://braincanada.ca/funded-grants/molecular-regulators-of-extracellular-matrix-remodeling-during-amyotrophic-lateral-sclerosisAmyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterised by the loss of motor neurons and the atrophy of muscles. Project Overview Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterised by the loss of motor neurons and the atrophy of...
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Momentum Grants program awards funding for bold brain research
https://braincanada.ca/about/news-updates/momentum-grants-program-awards-funding-for-bold-brain-researchPHOTO: Momentum Grant recipients (from left): Annie Ciernia, Michèle Desjardins, Mark Cembrowski, Stuart Trenholm and Mark Brandon. Brain Canada is proud to announce the five recipients of the Momentum Grants, a new program that enables researchers to build upon their previously funded Future...
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Monitoring and Modulation of Alpha Synuclein in Microglia: Implications for Parkinson’s Disease
https://braincanada.ca/funded-grants/monitoring-and-modulation-of-alpha-synuclein-in-microglia-implications-for-parkinson-s-diseaseIn this study, we. aim to do two things: 1) monitor the distribution of a-Syn in Parkinson’s disease (PD) context to understand the factors that can cause a-Syn to build-up in certain cells of the brain, called microglia. Project Overview In this study, we. aim to do two things: 1) monitor the...
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Montreal functional brain imaging platform
https://braincanada.ca/funded-grants/montreal-functional-brain-imaging-platformDr. Shmuel and his team are establishing a local platform which will support functional MRI (fMRI) in the alert non-human primate brain. Project Overview Dr. Shmuel and his team are establishing a local platform which will support functional MRI (fMRI) in the alert non-human primate brain. The...
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Montreal integrated neuropsychiatric cohort: Identifying subtypes of Autism and Schizophrenia integrating genomics, endophenotypes, and cohorts of high-risk genetic variants
https://braincanada.ca/funded-grants/montreal-integrated-neuropsychiatric-cohort-identifying-subtypes-of-autism-and-schizophrenia-integrating-genomics-endophenotypes-and-cohorts-of-high-risk-genetic-variantsAutism spectrum disorders (ASD) and schizophrenia (SZ) are two psychiatric conditions that affect approximately 2% of the general population. Genetic studies have identified mutations in hundreds of genes associated with ASD and SZ. Project Overview Autism spectrum disorders (ASD) and schizophrenia...