Directory of funded grants

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809 results found

Mechanistic Dissection of CD33 Isoforms within Microglia in Neurodegeneratio

  • Area of research

    Neurodegeneration

  • Disease Area

    Alzheimer’s

  • Competition

    Accelerator Grants: Neurodegeneration x Immunology

  • Province

    Alberta

  • Start Date

    2026

  • Total Grant Amount

    $300,000

  • Health Canada Contribution

    $150,000

Project Overview

Alzheimer’s disease is the most common cause of dementia and affects hundreds of thousands of Canadians. Both genetic and environmental factors contribute to its development, but recent research highlights the importance of the brain’s immune system—particularly a specialized immune cell type called microglia. Microglia help maintain brain health by removing…

Project Ongoing

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Comprehensive analysis of genetic interactions between HLA and APOE alleles for lipid and cognitive traits in large-scale cohorts 

  • Grant Type

    Team grants

  • Area of research

    Neurodegeneration

  • Disease Area

    Alzheimer’s

  • Competition

    Accelerator Grants: Neurodegeneration x Immunology

  • Province

    Québec

  • Start Date

    2026

  • Total Grant Amount

    $300,000

  • Health Canada Contribution

    $150,000

Project Overview

Prior research has shown that the immune system processes can influence risk of cognitive decline, but the exact mechanisms are not yet understood. Our hypothesis is that we can use genetics to better understand the relationship between the immune system and cognition. There is a set of immune-encoding genes (called…

Project Ongoing

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Shifting perspectives in Parkinson’s disease: can peripheral immune cells induce neurodegeneration without vascular transmigration

  • Grant Type

    Team grants

  • Area of research

    Neurodegeneration

  • Disease Area

    Parkinson's

  • Competition

    Accelerator Grants: Neurodegeneration x Immunology

  • Province

    Québec

  • Start Date

    2026

  • Total Grant Amount

    $300,000

  • Health Canada Contribution

    $150,000

Project Overview

Parkinson’s disease (PD) is the second most common neurodegenerative disorder in the world and affects over 100,000 Canadians. It causes movement difficulties and other symptoms that worsen over time. Although treatments can relieve symptoms, none can stop or slow the progression of the disease. Scientists have long focused on brain…

Project Ongoing

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Integrating multi-omics and neuroimaging to dissect crosstalk between the adaptive and innate immune systems in Alzheimer’s disease

  • Grant Type

    Team grants

  • Area of research

    Neurodegeneration

  • Disease Area

    Alzheimer’s

  • Competition

    Accelerator Grants: Neurodegeneration x Immunology

  • Province

    Québec

  • Start Date

    2026

  • Total Grant Amount

    $300,000

  • Health Canada Contribution

    $150,000

Project Overview

Alzheimer’s disease (AD) is the most common cause of dementia, affecting memory, thinking, and daily functioning. AD is characterized by the buildup of two proteins, amyloid-β and tau. Specifically, tau protein is responsible for the loss of brain cells, leading to dementia. In addition to these two proteins, however, studies…

Project Ongoing

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The small intestinal environment and Alzheimer’s Disease: a new frontier in the gut-brain axis

  • Grant Type

    Team grants

  • Area of research

    Neurodegeneration

  • Disease Area

    Alzheimer’s

  • Competition

    Accelerator Grants: Neurodegeneration x Immunology

  • Province

    Alberta

  • Start Date

    2026

  • Total Grant Amount

    $300,000

  • Health Canada Contribution

    $150,000

Project Overview

There is a lot of talk about the gut microbiome in neurology. This is important, because people with neurological diseases, including Alzheimer´s disease (AD), change their diets and think about probiotics when finding out about their diagnosis. Researchers study the gut microbiome by analyzing stool samples and then seeing if…

Project Ongoing

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