Directory of funded grants

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552 results found

Development of novel oligonucleotide delivery modalities for Huntington disease

  • Program Type

    Team grants

  • Area of research

    Neurodegeneration

  • Disease Area

    Other

  • Competition

    Brain Canada-Huntington Society of Canada Creating HD Clinician-Scientist-to-Patient Virtual Networks Multi-Investigator Research Initiative (MIRI)

  • Province

    British Columbia

  • Start Date

    2017

  • Total Grant Amount

    $950,000

  • Health Canada Contribution

    $475,000

Project Overview

Huntington disease (HD) is an inherited neurodegenerative disease that affects approximately 1 in 7500 individuals in the Western world. The cause of HD is a mutation in one copy of the HTT gene, which produces the toxic mutant huntingtin protein responsible for the brain cell loss associated with the disease.…

Project Ongoing

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Gangliosides in Huntington’s disease: from bench to clinics and back

  • Program Type

    Team grants

  • Area of research

    Neurodegeneration

  • Disease Area

    Other

  • Competition

    Brain Canada-Huntington Society of Canada Creating HD Clinician-Scientist-to-Patient Virtual Networks Multi-Investigator Research Initiative (MIRI)

  • Province

    Alberta

  • Start Date

    2016

  • Total Grant Amount

    $950,000

  • Health Canada Contribution

    $475,000

Project Overview

Huntington disease (HD) is an inherited disorder that causes progressive malfunctioning and death of parts of the brain that control movement, reasoning and emotions. HD patients also suffer from depression and personality changes.  There is no cure for HD. Symptoms progress steadily until patients can no longer conduct a normal…

Project Complete

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Northern Lights collaboration for better 2-photon probes

  • Program Type

    Team grants

  • Area of research

    Neurotechnology

  • Disease Area

    Other

  • Competition

    BRAIN Initiative

  • Province

    Alberta

  • Start Date

    2017

  • Total Grant Amount

    $413,162

  • Health Canada Contribution

    $206,581

Project Overview

The Northern Lights collaboration for better 2-photon probes will combine the expertise of four very different investigators and laboratories from Montana and Canada with complementary interests and skills to tackle a fundamental problem in imaging of the activity of the living brain. It is now well agreed that genetically encoded,…

Project Complete

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Summer School in Computational Sensory Motor Neuroscience (CoSMo)

  • Program Type

    Capacity building grants

  • Area of research

    Neurotechnology

  • Disease Area

    Other

  • Competition

    BRAIN Initiative

  • Province

    Ontario

  • Start Date

    2016

  • Total Grant Amount

    $194,000

  • Health Canada Contribution

    $97,000

Project Overview

Major breakthroughs in neuroscience have been achieved through the application of computational models to empirical research. Models are essential to connect theory to behavior and the increasingly rich and complex measures of nervous function at multiple spatial and temporal scales. That said, modeling is a highly complex activity requiring extensive…

Project Complete

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Prototype NIR Ca2+ indicators into refined tools that can be applied for neuronal activity imaging in model organisms

  • Program Type

    Team grants

  • Area of research

    Neurotechnology

  • Disease Area

    Other

  • Competition

    BRAIN Initiative

  • Province

    Alberta

  • Start Date

    2015

  • Total Grant Amount

    $246,996

  • Health Canada Contribution

    $123,498

Project Overview

One of the major challenges facing the BRAIN initiative is the development of technologies that will enable the recording of neural activity throughout the entire volume of a rodent brain. Optical imaging approaches for recording of neural activity in model organisms have already proven to be highly effective, but are…

Project Complete

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