Directory of funded grants

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444 results found

Distinct neuro-immune interactions drive sex differences  in chronic pain

  • Program Type

    Team grants

  • Area of research

    Central Nervous System

  • Disease Area

    Other

  • Competition

    2014 MIRI Team Grants

  • Province

    Québec

  • Start Date

    2015

  • Total Grant Amount

    $2,294,000

  • Health Canada Contribution

    $1,147,000

Project Overview

One of the most important advances in our understanding of chronic pain over the last decade or so is the realization that neurons are not the only cells in the central nervous system participating in the processing of pain signals. Immune-like "glial" cells (especially microglia and astrocytes), thought previously to…

Neurobiological correlates of TMS

  • Program Type

    Team grants

  • Area of research

    Central Nervous System

  • Disease Area

    Other

  • Competition

    2014 MIRI Team Grants

  • Province

    Ontario

  • Start Date

    2015

  • Total Grant Amount

    $865,517

  • Health Canada Contribution

    $432,759

Project Overview

Noninvasive brain stimulation is gaining acceptance as an alternate therapy for an increasing number of disorders, including major depression, schizophrenia, stroke and Parkinson’s disease. A form of noninvasive brain stimulation called transcranial magnetic stimulation (TMS) is less invasive and safer as compared to other brain stimulation therapies; however, lack of…

Canadian rTMS Treatment and Biomarker Network in Depression (CARTBIND) Trial

  • Program Type

    Team grants

  • Area of research

    Mental Health

  • Disease Area

    Mental illness

  • Competition

    2014 MIRI Team Grants

  • Province

    Ontario

  • Start Date

    2015

  • Total Grant Amount

    $1,387,500

  • Health Canada Contribution

    $693,750

Project Overview

Repetitive transcranial magnetic stimulation (rTMS) is an effective treatment for patients with depression who have not responded to antidepressant medications. rTMS involves stimulating the brain with a series of magnetic pulses delivered through a hand-held magnetic coil. Treatment duration is about 40 min and about 8-10 treatments per day can…

Stimulating Endogenous Regeneration of Photoreceptors as a Potential Cure for Blindness

  • Program Type

    Team grants

  • Area of research

    Central Nervous System

  • Disease Area

    Other

  • Competition

    2014 MIRI Team Grants

  • Province

    Ontario

  • Start Date

    2015

  • Total Grant Amount

    $1,387,869

  • Health Canada Contribution

    $693,935

Project Overview

Sight is the most precious sense, and patients suffering vision loss endure a devastating experience. Blindness often results from the gradual death of photoreceptors, the retinal cells that perceive light. Many researchers are attempting to replace lost cells through transplantation of stem cell-derived photoreceptors. However, integration of injected photoreceptors into…