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858 results found

Brain-heart dynamics in treatment-resistant depression and the effects of repetitive transcranial magnetic stimulation

Repetitive transcranial magnetic stimulation (rTMS) is a non-invasive neurostimulation therapy, recommended by Canadian guidelines as a first-line intervention for major depression that does not respond to an adequate course of pharmacological therapy, known as treatment-resistant depression (TRD).


Grant type
Capacity building grants
Area of Research
Mental Health
Competition
Rising Stars Trainee Awards
Province
British Columbia
Start Date
2024

Defective protein translation: a causative pathway in ALS

Amyotrophic lateral sclerosis (ALS) is a nervous system disease that affects nerve cells (motor neurons) connecting muscle with the brain and spinal cord.


Grant type
Capacity building grants
Area of Research
Neurodegeneration
Competition
Rising Stars Trainee Awards
Province
British Columbia
Start Date
2024

Characterizing the effects of blocking TDP-43 SUMOylation during cellular stress and recovery using live-cell imaging

A common feature in almost all ALS cases is the build up of a protein called TDP-43 in the brain and spinal cord.


Grant type
Capacity building grants
Area of Research
Neurodegeneration
Competition
Rising Stars Trainee Awards
Province
Ontario
Start Date
2024

A combined in-vivo ex-vivo approach to investigate imaging biomarkers in ALS diagnosis and aetiology

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder with no known cure, leading to progressive loss of motor function and ultimately death.


Grant type
Capacity building grants
Area of Research
Neurodegeneration
Competition
Rising Stars Trainee Awards
Province
Québec
Start Date
2024

Role of the gut microbiome-brain axis in sexual dimorphism of ALS

Males are twice as likely to develop ALS compared to females and the disease onset is also earlier in males than females.


Grant type
Capacity building grants
Area of Research
Neurodegeneration
Competition
Rising Stars Trainee Awards
Province
Alberta
Start Date
2024

Investigating the role of TDP-43 in DNA Replication: Implications for ALS Pathogenesis

Cells are constantly under stress due to several environmental and internal factors.


Grant type
Capacity building grants
Area of Research
Neurodegeneration
Competition
Rising Stars Trainee Awards
Province
Ontario
Start Date
2024

Investigating cerebellar pathology in a zebrafish C9orf72 ALS model

Amyotrophic Lateral Sclerosis (ALS) is a rare and fatal disease, which is characterized by degeneration of specific neurons called “Motor neurons” that control the movement of our muscles.


Grant type
Capacity building grants
Area of Research
Neurodegeneration
Competition
Rising Stars Trainee Awards
Province
Québec
Start Date
2024

Unravelling Molecular Mechanisms of ALS: Characterizing the in vitro and in vivo effects of biometals on the ALS-linked proteins TDP-43, SOD1, PGRN, and MFSD8

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by the degeneration of motor neurons, typically resulting from gene mutations that facilitate abnormal protein aggregation.


Grant type
Capacity building grants
Area of Research
Neurodegeneration
Competition
Rising Stars Trainee Awards
Province
Ontario
Start Date
2024

Multi-modal neuroimaging biomarkers of Parkinson’s disease progression

Parkinson’s disease (PD) is one of the most common neurodegenerative disorders in the world.


Grant type
Capacity building grants
Area of Research
Neurodegeneration
Competition
Rising Stars Trainee Awards
Province
Québec
Start Date
2024

Dissecting the shared origins of schizophrenia and chronic cannabis use: A genomic investigation

Regular cannabis use is indisputably linked to schizophrenia.


Grant type
Capacity building grants
Area of Research
Mental Health
Competition
Rising Stars Trainee Awards
Province
Ontario
Start Date
2024