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858 results found

Apolipoprotein receptor 2 in AD-related brain vessel dysfunction

What is the role of apolipoprotein receptor 2, a protein found in the brain vessels, in Alzheimer’s disease ?


Grant type
Capacity building grants
Area of Research
Neurodegeneration
Competition
Alzheimer's Association International Grant Program
Province
Alberta
Start Date
2024

Targeting KCC2 for rescuing functional impairments in Alzheimer’s disease

Within the brain, cells communicate by sending signals that either enhance or dampen the activity of other cells.


Grant type
Capacity building grants
Area of Research
Neurodegeneration
Competition
Alzheimer's Association International Grant Program
Province
Québec
Start Date
2024

Cognitive training platform to revolutionize healthcare for people with concussions

Led by Dr. Jocelyn Faubert from the Université de Montréal in collaboration with Neurotracker Athletics Inc., this project includes an inter-provincial research collaboration with Prof. Brian Christie and Prof. Jodie Gawryluk from the University of Victoria.


Grant type
Platform grants
Area of Research
Injury
Competition
CQDM - Brain Canada - Quantum Leap
Province
Québec
Start Date
2024

A novel immunotherapy based on genetically modified hematopoietic stem cells as a new hope for treating glioblastoma, an aggressive cancerous tumor of the brain

Led by Dr. Elie Haddad from CHU Sainte-Justine in collaboration with Immugenia, this project includes an inter-provincial research collaboration


Grant type
Platform grants
Area of Research
Cancer
Competition
CQDM - Brain Canada - Quantum Leap
Province
Québec
Start Date
2024

The application of 3D models to assess the role of microglia in neurodegenerative disorders

Challenge: Alzheimer’s disease (AD) is characterized by a decline in cognitive function, yet it is now widely acknowledged that as the disease advances, dopaminergic neurons in the midbrain become particularly vulnerable, leading to non-cognitive symptoms such as motor dysfunction.


Grant type
Platform grants
Area of Research
Neurodegeneration
Competition
CQDM - Brain Canada - Quantum Leap
Province
Québec
Start Date
2024

Precision Metabolism: Deciphering and Targeting Metabolic Adaptations in Therapy-Resistant Recurrent Glioblastoma

Glioblastoma (GBM) is a common and deadly brain cancer in adults.


Grant type
Capacity building grants
Area of Research
Cancer
Competition
CRS Operating Grants
Province
Manitoba
Start Date
2024

Targeting the immune suppressive microenvironment in histone 3-mutant high-grade gliomas

The immune system is responsible for protecting the body against diseases, but it can also play a role in tumor formation.


Grant type
Capacity building grants
Area of Research
Cancer
Competition
CRS Operating Grants
Province
Québec
Start Date
2024

Impact of 2-hydroxyglutarate-induced astrocytes reactivity in low-grade glioma progression and recurrence

Mutations in the metabolic enzymes are commonly observed in brain cancers.


Grant type
Capacity building grants
Area of Research
Cancer
Competition
CRS Operating Grants
Province
Québec
Start Date
2024

Specific translation of mRNAs encoding primary cilia components as a new resistance mechanism in glioblastoma

We are studying a type of brain tumour called glioblastoma (GBM), which is often fatal despite current treatments.


Grant type
Capacity building grants
Area of Research
Cancer
Competition
CRS Operating Grants
Province
Ontario
Start Date
2024

Identification of the Neural Circuitry of Persistent Depressive Symptoms in First-Episode Schizophrenia: From Biomarkers to Predictive Imaging

People with schizophrenia often suffer from depressive and negative symptoms, such as reduced emotional expression, or less motivation.


Grant type
Capacity building grants
Area of Research
Mental Health
Competition
Rising Stars Trainee Awards
Province
Ontario
Start Date
2024