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858 results found

A physiologic-to-tissue level approach to characterize the pathophysiology of hypoxic ischemic brain injury in humans.

During a cardiac arrest, when the heart stops beating, blood flow and the delivery of the oxygen to the brain stops.


Grant type
Capacity building grants
Area of Research
Injury
Competition
Future Leaders in Canadian Brain Research
Province
British Columbia
Start Date
2024

Human choroid plexus organoids to investigate unexplored mechanisms and secreted biomarkers in neurodevelopmental disease

Our brains are built by neural stem cells (NSCs), which produce all the neurons and other specialized cells that form the brain and execute its functions.


Grant type
Capacity building grants
Area of Research
Neurodegeneration
Competition
Future Leaders in Canadian Brain Research
Province
British Columbia
Start Date
2024

Dissecting brain-wide functional circuits underlying social decision making by developing a naturalistic virtual reality platform of juvenile zebrafish

Understanding how the brain works when we make decisions during social interactions has been difficult for neuroscientists.


Grant type
Capacity building grants
Area of Research
Central Nervous System
Competition
Future Leaders in Canadian Brain Research
Province
Ontario
Start Date
2024

Understanding brain development and maintenance via spatial transcriptomics

We identified changes in the gene called IRF2BPL (Interferon Regulatory Factor 2 Binding Protein Like) as the cause of a severe brain disorder in children called NEDAMSS (Neurodevelopmental disorder with abnormal movements, loss of speech and seizures).


Grant type
Capacity building grants
Area of Research
Neurodevlopment
Competition
Future Leaders in Canadian Brain Research
Province
Manitoba
Start Date
2024

A unifying approach to treat multisystem proteinopathy and ALS using noninvasive novel ASO delivery

Multisystem proteinopathy (MSP) is a devastating rare disease described by a cluster of diseases that affect the brain, bone, and muscle.


Grant type
Capacity building grants
Area of Research
Neurodegeneration
Competition
Future Leaders in Canadian Brain Research
Province
Ontario
Start Date
2024

Molecular regulators of extracellular matrix remodeling during Amyotrophic Lateral Sclerosis

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterised by the loss of motor neurons and the atrophy of muscles.


Grant type
Capacity building grants
Area of Research
Neurodegeneration
Competition
Future Leaders in Canadian Brain Research
Province
Québec
Start Date
2024

Imaging Endocannabinoid Signalling in Individuals with Cocaine Addiction

Cocaine is a highly addictive stimulant drug. Approximately 10% of Canadians aged 20-24 report current cocaine use.


Grant type
Capacity building grants
Area of Research
Mental Health
Competition
Future Leaders in Canadian Brain Research
Start Date
2024

Does the Epstein-Barr virus activate immune cells before multiple sclerosis becomes symptomatic?

Multiple Sclerosis (MS) is a serious chronic neurological condition, particularly common among young adults in Canada.


Grant type
Capacity building grants
Area of Research
Neurodegeneration
Competition
Future Leaders in Canadian Brain Research
Province
Ontario
Start Date
2024

Development of Genetic Screening Platforms for Immune Evasion in Glioblastoma

In 2023, over 3,000 Canadians were newly diagnosed as brain tumor, and around 2,500 succumbed to this disease.


Grant type
Capacity building grants
Area of Research
Cancer
Competition
Future Leaders in Canadian Brain Research
Province
Québec
Start Date
2024

Interrogating the role of glial development in models of attention deficit hyperactivity disorder

Attention-deficit hyperactivity disorder (ADHD) is the most common disorder that impacts development of the brain.


Grant type
Capacity building grants
Area of Research
Neurodevlopment
Competition
Future Leaders in Canadian Brain Research
Start Date
2024