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839 results found

Challenging epigenetic hallmarks of aging in the choroid plexus to improve brain homeostasis

The choroid plexus (CP) is a secretory tissue found in each of the brain ventricles.


Grant type
Capacity building grants
Area of Research
Neurodegeneration
Competition
Future Leaders in Canadian Brain Research
Province
Québec
Start Date
2021

Understanding how deviations in postnatal hippocampal neurogenesis and circuit activity contribute to bipolar disorder with patient-derived pluripotent stem cells

The brain is vulnerable to many disorders that can strike at every stage of life.


Grant type
Capacity building grants
Area of Research
Neurodevlopment
Competition
Future Leaders in Canadian Brain Research
Province
Ontario
Start Date
2021

Circadian control of microglial activation in chronic pain states

Circadian, or 24-hour, rhythms control almost all biological systems in our bodies with sleep-wake cycles and body temperature control the best known examples.


Grant type
Capacity building grants
Area of Research
Central Nervous System
Competition
Future Leaders in Canadian Brain Research
Province
Ontario
Start Date
2021

Modulating attentional circuitry in the anterior cingulate cortex using adaptive intracranial stimulation

Attention is an incompletely understood, complex process that requires precise coordination of brain rhythms within the anterior cingulate cortex (ACC).


Grant type
Capacity building grants
Area of Research
Central Nervous System
Competition
Future Leaders in Canadian Brain Research
Province
Ontario
Start Date
2021

Neural Basis Underlying the Transition Between Attention States

How do we seamlessly transition between reading a novel and reminiscing our last vacation before the pandemic?


Grant type
Capacity building grants
Area of Research
Central Nervous System
Competition
Future Leaders in Canadian Brain Research
Province
Alberta
Start Date
2021

Portable Low Field MRI for Application in Multiple Sclerosis

Multiple Sclerosis (MS) is a disease that attacks the nerves in the brain, making it difficult for the brain to send signals to the rest of the body. MS symptoms are extremely variable, and can include difficulty walking, fatigue, pain, and cognitive issues such as problems with concentration, memory and word-finding.


Grant type
Capacity building grants
Area of Research
Neurodegeneration
Competition
Future Leaders in Canadian Brain Research
Province
British Columbia
Start Date
2021

Characterizing the roles of synapse organizers in mediating synaptic function and brain-based diseases

The human brain is made up of neural circuits that are thought to underlie all brain function.


Grant type
Capacity building grants
Area of Research
Neurodevlopment
Competition
Shireen and Edna Marcus Excellence Award
Province
British Columbia
Start Date
2021

Investigating the role of mutations in CHCHD10 using ALS cell and zebrafish genetic models

CHCHD10 is a nuclear encoded mitochondrial protein of the twin Cx9C family whose cellular function remains to be fully understood.


Grant type
Team grants
Area of Research
Neurodegeneration
Competition
ALS Canada - Brain Canada Discovery Grants
Province
Québec
Start Date
2021

The Lived Experience of Autism in an Indigenous Community: A Qualitative Study

Autism spectrum disorder (ASD) is characterized by difficulties with communication, social deficits as well as repetitive behaviors and interests.


Grant type
Capacity building grants
Area of Research
Other
Competition
Shireen and Edna Marcus Excellence Award
Province
Alberta
Start Date
2021

Identifying the cell-type specific transcriptional program by Npas4 in motor learning

The primary motor cortex in the brain is responsible for voluntary movement. It has also been proposed to be one of the sites for motor memory formation and storage.


Grant type
Capacity building grants
Area of Research
Injury
Competition
Future Leaders in Canadian Brain Research
Province
Ontario
Start Date
2021