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Increased metabolism (hypermetabolism) is a characteristic often associated with more aggressive, faster progressing cases of ALS.

Recently, Dr. Honglin Luo, in collaboration with Dr. Neil Cashman, discovered that mutations in the ALS-linked SOD1 gene result in activation of a specific neuroinflammatory pathway called cGAS-STING.

Amyotrophic lateral sclerosis (ALS) is a late-onset neurodegenerative disease with distinct genetic contributions.

Amyotrophic Lateral Sclerosis (ALS) is very much a disease of losses and adjustments.

Mutations in a gene called C9ORF72 are the most common genetic cause of ALS. These mutations are unique in that unlike most other ALS-linked genes, where there is often a mistake in a single piece of DNA, C9ORF72 mutations involve a section of DNA that is abnormally repeated hundreds or even thousands of times.

CHCHD10 is a nuclear encoded mitochondrial protein of the twin Cx9C family whose cellular function remains to be fully understood.

Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease, primarily affecting motor neurons, for which there are currently no adequately effective therapies.

In Canada, 1 in 20 people live with depression. Substantial efforts have been made over the years to develop new treatments to enhance therapeutic options.

The brain is more than the sum of its parts.

Spinal cord injury (SCI) is a devastating medical condition that forever changes the trajectory of life.