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839 results found

Drug Delivery across the Human Blood-Brain Barrier

Toxic amyloid proteins are known to be a significant contributing factor in the development of Alzheimer’s disease.


Grant type
Platform grants
Area of Research
Neurodegeneration
Competition
CQDM - Brain Canada - Focus on Brain
Province
Ontario
Start Date
2015

Cyto-iGluSnFR: A glutamate biosensor platform for brain diseases

The team wants to take a new breakthrough technology called Cyto-iGluSnFR (pronounced “sight-oh-eye-glue-sniffer”) and adapt it for the discovery of drugs to treat a variety of brain and eye diseases.


Grant type
Platform grants
Area of Research
Neurotechnology
Competition
CQDM - Brain Canada - Focus on Brain
Province
Québec
Start Date
2015

‘Best in Class’ Platform for Blood Brain Barrier Delivery of Therapeutics

The blood-brain barrier (BBB) plays an essential role in protecting the brain from blood-borne diseases.


Grant type
Platform grants
Area of Research
Multiple
Competition
CQDM - Brain Canada - Focus on Brain
Province
Ontario
Start Date
2015

Preclinical development of a disease modifying small molecule therapy for Alzheimer disease

No medications exist that can stop or even slow the progression for Alzheimer Disease (AD).


Grant type
Team grants
Area of Research
Neurodegeneration
Competition
BC Alzheimer's Research Award Program
Province
British Columbia
Start Date
2015

Modulating memory circuits: focal DBS treatments to improve medial temporal lobe function

Two diseases that show very different trajectories have nevertheless led researchers to identify dysfunction in a common brain network.


Grant type
Team grants
Area of Research
Multiple
Competition
2015 MIRI Team Grants
Province
Ontario
Start Date
2015

Biomarkers for Crossing the Translational Divide in Acute Spinal Cord Injury

Each year, over 1,500 Canadians sustain an acute spinal cord injury (SCI), and join close to 40,000 across our nation living with one of the most physically and psychologically devastating of injuries.


Grant type
Team grants
Area of Research
Injury
Competition
2014 MIRI Team Grants
Province
British Columbia
Start Date
2015

Adolescent Mental Health

Most mental disorders begin in adolescence; however, there are many gaps in our understanding of youth mental health.


Grant type
Team grants
Area of Research
Mental Health
Competition
2014 MIRI Team Grants
Province
Alberta
Start Date
2015

Stimulating Endogenous Regeneration of Photoreceptors as a Potential Cure for Blindness

Sight is the most precious sense, and patients suffering vision loss endure a devastating experience. Blindness often results from the gradual death of photoreceptors, the retinal cells that perceive light.


Grant type
Team grants
Area of Research
Central Nervous System
Competition
2014 MIRI Team Grants
Province
Ontario
Start Date
2015

Canadian rTMS Treatment and Biomarker Network in Depression (CARTBIND) Trial

Repetitive transcranial magnetic stimulation (rTMS) is an effective treatment for patients with depression who have not responded to antidepressant medications.


Grant type
Team grants
Area of Research
Mental Health
Competition
2014 MIRI Team Grants
Province
Ontario
Start Date
2015

Neurobiological correlates of TMS

Noninvasive brain stimulation is gaining acceptance as an alternate therapy for an increasing number of disorders, including major depression, schizophrenia, stroke and Parkinson’s disease.


Grant type
Team grants
Area of Research
Central Nervous System
Competition
2014 MIRI Team Grants
Province
Ontario
Start Date
2015