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886 results found

Distinct neuro-immune interactions drive sex differences in chronic pain

One of the most important advances in our understanding of chronic pain over the last decade or so is the realization that neurons are not the only cells in the central nervous system participating in the processing of pain signals.


Grant type
Team grants
Area of Research
Central Nervous System
Competition
2014 MIRI Team Grants
Province
Québec
Start Date
2015

Canadian rTMS Treatment and Biomarker Network in Depression (CARTBIND) Trial

Repetitive transcranial magnetic stimulation (rTMS) is an effective treatment for patients with depression who have not responded to antidepressant medications.


Grant type
Team grants
Area of Research
Mental Health
Competition
2014 MIRI Team Grants
Province
Ontario
Start Date
2015

2015 Barbara Turnbull Award for Spinal Cord Research

Dr. David and his research team are studying the mechanisms that control the delivery and release of iron in the nervous system.


Grant type
Capacity building grants
Area of Research
Injury
Competition
Barbara Turnbull Award for Spinal Cord Research
Province
Québec
Start Date
2015

Human MiniPromoters for Restricted Expression of Ocular Gene Therapy

The purpose of this project is to develop promoters. Promoters are pieces of DNA, which act as switches to turn genes on and off.


Grant type
Platform grants
Area of Research
Sensory System
Competition
CQDM - Brain Canada - Focus on Brain
Province
British Columbia
Start Date
2015

‘Best in Class’ Platform for Blood Brain Barrier Delivery of Therapeutics

The blood-brain barrier (BBB) plays an essential role in protecting the brain from blood-borne diseases.


Grant type
Platform grants
Area of Research
Multiple
Competition
CQDM - Brain Canada - Focus on Brain
Province
Ontario
Start Date
2015

Cyto-iGluSnFR: A glutamate biosensor platform for brain diseases

The team wants to take a new breakthrough technology called Cyto-iGluSnFR (pronounced “sight-oh-eye-glue-sniffer”) and adapt it for the discovery of drugs to treat a variety of brain and eye diseases.


Grant type
Platform grants
Area of Research
Neurotechnology
Competition
CQDM - Brain Canada - Focus on Brain
Province
Québec
Start Date
2015

Preclinical development of a disease modifying small molecule therapy for Alzheimer disease

No medications exist that can stop or even slow the progression for Alzheimer Disease (AD).


Grant type
Team grants
Area of Research
Neurodegeneration
Competition
BC Alzheimer's Research Award Program
Province
British Columbia
Start Date
2015

Modulating memory circuits: focal DBS treatments to improve medial temporal lobe function

Two diseases that show very different trajectories have nevertheless led researchers to identify dysfunction in a common brain network.


Grant type
Team grants
Area of Research
Multiple
Competition
2015 MIRI Team Grants
Province
Ontario
Start Date
2015

Understanding stress to improve mental health

Recent estimates indicate that 1 in 5 Canadians are affected annually by mood, anxiety and other mental illnesses.


Grant type
Team grants
Area of Research
Mental Health
Competition
2014 MIRI Team Grants
Province
Alberta
Start Date
2015

Targeting the Synaptic Pathway in Neurodevelopmental and Psychiatric Disorders

Autism spectrum disorders are neurodevelopmental disorders characterized by deficits in social interaction, poor communication, and restricted, stereotyped patterns of behavior.


Grant type
Team grants
Area of Research
Multiple
Competition
2014 MIRI Team Grants
Province
British Columbia
Start Date
2015