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839 results found

A brain-specific approach to RNA therapeutics: developing a novel protein delivery strategy for the central nervous system

Challenge: Delivery of therapeutic proteins to the brain has been a longstanding barrier to CNS drug
development.

Project ongoing See Project & Researchers
Area of Research
Central Nervous System
Competition
CQDM - Brain Canada - Call for Collaborative Research Projects on the Brain
Province
Québec
Start Date
2025

Novel Repetitive Transcranial Magnetic Stimulation Paradigm to Reduce Cortical Hyperexcitability in Patients with ALS

ALS is a devastating neurological disease characterized by the progressive degeneration of motor neurons leading to paralysis and death.

Project ongoing See Project & Researchers
Area of Research
Neurodegeneration
Competition
ALS Canada - Brain Canada Discovery Grants
Province
Ontario
Start Date
2025

Trajectoires cérébrales normatives et atypiques : repenser le suivi du neurodéveloppement pédiatrique

Les commotions cérébrales chez les enfants sont un problème de santé publique majeur en raison de leur impact à long terme sur le développement cognitif et socio-émotionnel.

Project ongoing See Project & Researchers
Grant type
Capacity building grants
Area of Research
Neurodevlopment
Competition
Future Leaders in Canadian Brain Research
Province
Québec
Start Date
2025

Phenotyping of Alzheimer’s disease across imaging-defined stages of cerebral amyloid angiopathy

Mixed dementia is the most common form of dementia.

Project ongoing See Project & Researchers
Grant type
Capacity building grants
Area of Research
Neurodegeneration
Competition
Future Leaders in Canadian Brain Research
Province
Ontario
Start Date
2025

Understanding cerebral blood flow control in humans after cannabis use

Cannabis is one of the most commonly used recreational substances in Canada, yet its effects on brain blood flow remain poorly understood.

Project ongoing See Project & Researchers
Grant type
Capacity building grants
Area of Research
Central Nervous System
Competition
Future Leaders in Canadian Brain Research
Province
Ontario
Start Date
2025

Identifying Proteogenomic Signatures Of Smoldering Lesions in Multiple Sclerosis

Multiple sclerosis (MS) is the most common cause of non-traumatic neurological disability, affecting 1 in 400 Canadian adults.

Project ongoing See Project & Researchers
Grant type
Capacity building grants
Area of Research
Central Nervous System
Competition
Future Leaders in Canadian Brain Research
Province
Québec
Start Date
2025

Dual-Actuated Acoustic Microbubble Microrobots for Targeted and Precision Brain Tumour Treatment

Glioblastoma is one of the most aggressive brain cancers, with very few treatment options and a poor survival rate.

Project ongoing See Project & Researchers
Grant type
Capacity building grants
Area of Research
Cancer
Competition
Future Leaders in Canadian Brain Research
Province
Ontario
Start Date
2025

New function for DEPTOR tyrosine 289 phosphorylation in glioma metabolism

Deregulation of brain cell metabolism is commonly observed in low-grade brain cancers.

Project ongoing See Project & Researchers
Area of Research
Cancer
Competition
CRS Operating Grants
Province
Québec
Start Date
2025

Proteomic associations with brain and cognitive health and their interactions with modifiable risk factors for dementia

As people live longer, our society undergoes rapid demographic change.

Project ongoing See Project & Researchers
Grant type
Capacity building grants
Area of Research
Neurodegeneration
Competition
Future Leaders in Canadian Brain Research
Province
Ontario
Start Date
2025

Vascular innervation and blood-brain barrier dysfunction in Huntington’s disease using human iPSC-derived vascularized brain organoids.

“Vascular pathology, such as loss of neurovascular coupling and disruption of the blood-brain barrier (BBB), has been documented in Huntington’s disease (HD).

Project ongoing See Project & Researchers
Area of Research
Neurodegeneration
Competition
Huntington Society of Canada - Brain Canada Undergraduate Student Fellowship
Province
Québec
Start Date
2025